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@ARTICLE{Krall:154148,
author = {Krall, S. C. and Rottschy, C. and Oberwelland, E. and
Bzdok, D. and Fox, P. T. and Eickhoff, Simon and Fink, G. R.
and Konrad, K.},
title = {{T}he role of the right temporoparietal junction in
attention and social interaction as revealed by {ALE}
meta-analysis.},
journal = {Brain structure $\&$ function},
volume = {220},
number = {2},
issn = {1863-2661},
address = {Berlin},
publisher = {Springer},
reportid = {FZJ-2014-03541},
pages = {587-604},
year = {2015},
abstract = {The right temporoparietal junction (rTPJ) is frequently
associated with different capacities that to shift attention
to unexpected stimuli (reorienting of attention) and to
understand others' (false) mental state [theory of mind
(ToM), typically represented by false belief tasks].
Competing hypotheses either suggest the rTPJ representing a
unitary region involved in separate cognitive functions or
consisting of subregions subserving distinct processes. We
conducted activation likelihood estimation (ALE)
meta-analyses to test these hypotheses. A conjunction
analysis across ALE meta-analyses delineating regions
consistently recruited by reorienting of attention and false
belief studies revealed the anterior rTPJ, suggesting an
overarching role of this specific region. Moreover, the
anatomical difference analysis unravelled the posterior rTPJ
as higher converging in false belief compared with
reorienting of attention tasks. This supports the concept of
an exclusive role of the posterior rTPJ in the social
domain. These results were complemented by meta-analytic
connectivity mapping (MACM) and resting-state functional
connectivity (RSFC) analysis to investigate whole-brain
connectivity patterns in task-constrained and task-free
brain states. This allowed for detailing the functional
separation of the anterior and posterior rTPJ. The
combination of MACM and RSFC mapping showed that the
posterior rTPJ has connectivity patterns with typical ToM
regions, whereas the anterior part of rTPJ co-activates with
the attentional network. Taken together, our data suggest
that rTPJ contains two functionally fractionated subregions:
while posterior rTPJ seems exclusively involved in the
social domain, anterior rTPJ is involved in both, attention
and ToM, conceivably indicating an attentional shifting role
of this region.},
cin = {INM-1 / INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:24915964},
UT = {WOS:000350350300001},
doi = {10.1007/s00429-014-0803-z},
url = {https://juser.fz-juelich.de/record/154148},
}