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@ARTICLE{Kohl:154214,
author = {Kohl, S. and Wolters, Carolin and Gruendler, Theo O. J. and
Vogeley, Kai and Klosterkötter, Joachim and Kuhn, Jens},
title = {{P}repulse {I}nhibition of the {A}coustic {S}tartle
{R}eflex in {H}igh {F}unctioning {A}utism},
journal = {PLoS one},
volume = {9},
number = {3},
issn = {1932-6203},
address = {Lawrence, Kan.},
publisher = {PLoS},
reportid = {FZJ-2014-03593},
pages = {e92372 -},
year = {2014},
abstract = {High functioning autism is an autism spectrum disorder that
is characterized by deficits in social interaction and
communication as well as repetitive and restrictive behavior
while intelligence and general cognitive functioning are
preserved. According to the weak central coherence account,
individuals with autism tend to process information
detail-focused at the expense of global form. This
processing bias might be reflected by deficits in
sensorimotor gating, a mechanism that prevents
overstimulation during the transformation of sensory input
into motor action. Prepulse inhibition is an operational
measure of sensorimotor gating, which indicates an extensive
attenuation of the startle reflex that occurs when a
startling pulse is preceded by a weaker stimulus, the
prepulse.},
cin = {INM-3},
ddc = {500},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {333 - Pathophysiological Mechanisms of Neurological and
Psychiatric Diseases (POF2-333) / 89572 - (Dys-)function and
Plasticity (POF2-89572)},
pid = {G:(DE-HGF)POF2-333 / G:(DE-HGF)POF2-89572},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000333259900128},
pubmed = {pmid:24643088},
doi = {10.1371/journal.pone.0092372},
url = {https://juser.fz-juelich.de/record/154214},
}