000154324 001__ 154324
000154324 005__ 20220930130030.0
000154324 0247_ $$2doi$$a10.1016/j.nicl.2014.05.017
000154324 0247_ $$2Handle$$a2128/5829
000154324 0247_ $$2WOS$$aWOS:000349667800006
000154324 0247_ $$2altmetric$$aaltmetric:2410471
000154324 0247_ $$2pmid$$apmid:24967158
000154324 037__ $$aFZJ-2014-03672
000154324 082__ $$a610
000154324 1001_ $$0P:(DE-Juel1)156353$$aNiessen, E.$$b0$$eCorresponding Author$$ufzj
000154324 245__ $$aApraxia, pantomime and the parietal cortex
000154324 260__ $$a[Amsterdam u.a.]$$bElsevier$$c2014
000154324 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s154324
000154324 3367_ $$2DataCite$$aOutput Types/Journal article
000154324 3367_ $$00$$2EndNote$$aJournal Article
000154324 3367_ $$2BibTeX$$aARTICLE
000154324 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000154324 3367_ $$2DRIVER$$aarticle
000154324 520__ $$aApraxia, a disorder of higher motor cognition, is a frequent and outcome-relevant sequel of left hemispheric stroke. Deficient pantomiming of object use constitutes a key symptom of apraxia and is assessed when testing for apraxia. To date the neural basis of pantomime remains controversial. We here review the literature and perform a meta-analysis of the relevant structural and functional imaging (fMRI/PET) studies.Based on a systematic literature search, 10 structural and 12 functional imaging studies were selected.Structural lesion studies associated pantomiming deficits with left frontal, parietal and temporal lesions. In contrast, functional imaging studies associate pantomimes with left parietal activations, with or without concurrent frontal or temporal activations. Functional imaging studies that selectively activated parietal cortex adopted the most stringent controls.In contrast to previous suggestions, current analyses show that both lesion and functional studies support the notion of a left-hemispheric fronto-(temporal)-parietal network underlying pantomiming object use. Furthermore, our review demonstrates that the left parietal cortex plays a key role in pantomime-related processes. More specifically, stringently controlled fMRI-studies suggest that in addition to storing motor schemas, left parietal cortex is also involved in activating these motor schemas in the context of pantomiming object use. In addition to inherent differences between structural and functional imaging studies and consistent with the dedifferentiation hypothesis, the age difference between young healthy subjects (typically included in functional imaging studies) and elderly neurological patients (typically included in structural lesion studies) may well contribute to the finding of a more distributed representation of pantomiming within the motor-dominant left hemisphere in the elderly
000154324 536__ $$0G:(DE-HGF)POF2-333$$a333 - Pathophysiological Mechanisms of Neurological and Psychiatric Diseases (POF2-333)$$cPOF2-333$$fPOF II$$x0
000154324 536__ $$0G:(DE-HGF)POF2-89572$$a89572 - (Dys-)function and Plasticity (POF2-89572)$$cPOF2-89572$$fPOF II T$$x1
000154324 588__ $$aDataset connected to CrossRef, juser.fz-juelich.de
000154324 7001_ $$0P:(DE-Juel1)131720$$aFink, G. R.$$b1$$ufzj
000154324 7001_ $$0P:(DE-Juel1)131748$$aWeiss-Blankenhorn, Peter$$b2$$ufzj
000154324 773__ $$0PERI:(DE-600)2701571-3$$a10.1016/j.nicl.2014.05.017$$gVol. 5, p. 42 - 52$$p42 - 52$$tNeuroImage: Clinical$$v5$$x2213-1582$$y2014
000154324 8564_ $$uhttps://juser.fz-juelich.de/record/154324/files/FZJ-2014-03672.pdf$$yOpenAccess
000154324 8564_ $$uhttps://juser.fz-juelich.de/record/154324/files/FZJ-2014-03672.jpg?subformat=icon-144$$xicon-144$$yOpenAccess
000154324 8564_ $$uhttps://juser.fz-juelich.de/record/154324/files/FZJ-2014-03672.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
000154324 8564_ $$uhttps://juser.fz-juelich.de/record/154324/files/FZJ-2014-03672.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
000154324 8767_ $$92014-06-09$$d2014-07-03$$eAPC$$jZahlung erfolgt
000154324 909CO $$ooai:juser.fz-juelich.de:154324$$popenCost$$pVDB$$pdriver$$pOpenAPC$$popen_access$$popenaire$$pdnbdelivery
000154324 915__ $$0LIC:(DE-HGF)CCBY3$$2HGFVOC$$aCreative Commons Attribution CC BY 3.0
000154324 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000154324 915__ $$0StatID:(DE-HGF)0040$$2StatID$$aPeer review unknown
000154324 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000154324 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000154324 9141_ $$y2014
000154324 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)156353$$aForschungszentrum Jülich GmbH$$b0$$kFZJ
000154324 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich GmbH$$b1$$kFZJ
000154324 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131748$$aForschungszentrum Jülich GmbH$$b2$$kFZJ
000154324 9132_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0
000154324 9131_ $$0G:(DE-HGF)POF2-333$$1G:(DE-HGF)POF2-330$$2G:(DE-HGF)POF2-300$$3G:(DE-HGF)POF2$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lFunktion und Dysfunktion des Nervensystems$$vPathophysiological Mechanisms of Neurological and Psychiatric Diseases$$x0
000154324 9131_ $$0G:(DE-HGF)POF2-89572$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$v(Dys-)function and Plasticity$$x1
000154324 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0
000154324 9801_ $$aFullTexts
000154324 980__ $$ajournal
000154324 980__ $$aVDB
000154324 980__ $$aUNRESTRICTED
000154324 980__ $$aFullTexts
000154324 980__ $$aI:(DE-Juel1)INM-3-20090406
000154324 980__ $$aAPC