000154644 001__ 154644
000154644 005__ 20240313095011.0
000154644 037__ $$aFZJ-2014-03928
000154644 1001_ $$0P:(DE-Juel1)145394$$aZehl, Lyuba$$b0$$eCorresponding Author
000154644 1112_ $$aAREADNE 2014$$cSantorini$$d2014-06-25 - 2014-06-29$$wGreece
000154644 245__ $$aMetadata management for complex neurophysiological experiments
000154644 260__ $$c2014
000154644 3367_ $$0PUB:(DE-HGF)1$$2PUB:(DE-HGF)$$aAbstract$$babstract$$mabstract$$s1409229095_6671
000154644 3367_ $$033$$2EndNote$$aConference Paper
000154644 3367_ $$2DataCite$$aOutput Types/Conference Abstract
000154644 3367_ $$2ORCID$$aOTHER
000154644 3367_ $$2DRIVER$$aconferenceObject
000154644 3367_ $$2BibTeX$$aINPROCEEDINGS
000154644 500__ $$aAcknowledgments: SMHB, HBP (EU grant 604102), G-Node (BMBF Grant 01GQ1302), BrainScaleS (EU Grant269912), ANR-GRASP, Neuro_IC2010, CNRS-PEPS, Riken-CNRS Research Agreement. References: [1] Grewe J, Wachtler T, and Benda J (2011) Front. Neuroinform. 5:16[2] Riehle A, Wirtssohn S, Grün S, and Brochier T (2013) Front. Neural Circuits 7:48
000154644 520__ $$aTechnological progress in neuroscience allows recording from tens to hundreds of neuronssimultaneously, both in vitro and in vivo, using various recording techniques (e.g., multi-electrode recordings) and stimulation methods (e.g., optogenetics). In addition, recordingscan be performed in parallel from multiple brain areas, under more or less naturalconditions in (almost) freely behaving animals. Consequently, electrophysiologicalexperiments become increasingly complex. Moreover, to disentangle the relationship tobehavior, it is necessary to document animal training, experimental procedures, and detailsof the setup along with recorded neuronal and behavioral data. Considering this, availabilityof the information about the experimental conditions, commonly referred to as metadata, isof extreme relevance for reproducible data analysis and correct interpretation of results.Typically, experimenters have developed their own personal procedure to document theirexperiment, allowing at best other members of the lab to share data and metadata.However, at the latest when it comes to data sharing across labs, details may be missed. Inparticular if collaborating groups have different scientific backgrounds, implicit knowledge isoften not communicated. In order to perform interpretable analysis, each data set shouldtherefore clearly link to metadata annotations about experimental conditions such as theperformed task, quality of the data, or relevant preprocessing (e.g., spike sorting).In order to provide metadata in an organized, easily accessible, but also machine-readableway, an XML based file format, odML (open metadata Markup Language), was proposed [1].Here we will demonstrate the usefulness of standardized metadata collections for handlingthe data and their analysis in the context of a complex behavioral (reach to grasp)experiment with neuronal recordings from a large number of electrodes (Utah array)delivering massively parallel spike and LFP data [2]. We illustrate the conceptual design ofan odML metadata structure and provide a practical introduction on how to generate anodML file. In addition, we offer odML templates to facilitate the usage of odML acrossdifferent laboratories and experimental contexts. We demonstrate hands-on the advantagesof using odML to screen large numbers of data sets according to selection criteria (e.g.,behavioral performance) relevant for subsequent analyses (see companion posters byDenker et al. and Riehle et al.). Well organized metadata management is a key componentto guarantee reproducibility of experiments and to track provenance of performed analyses.
000154644 536__ $$0G:(DE-HGF)POF2-331$$a331 - Signalling Pathways and Mechanisms in the Nervous System (POF2-331)$$cPOF2-331$$fPOF II$$x0
000154644 536__ $$0G:(EU-Grant)269921$$aBRAINSCALES - Brain-inspired multiscale computation in neuromorphic hybrid systems (269921)$$c269921$$fFP7-ICT-2009-6$$x1
000154644 536__ $$0G:(EU-Grant)604102$$aHBP - The Human Brain Project (604102)$$c604102$$fFP7-ICT-2013-FET-F$$x2
000154644 536__ $$0G:(DE-Juel1)HGF-SMHB-2013-2017$$aSMHB - Supercomputing and Modelling for the Human Brain (HGF-SMHB-2013-2017)$$cHGF-SMHB-2013-2017$$fSMHB$$x3
000154644 536__ $$0G:(DE-HGF)POF2-89571$$a89571 - Connectivity and Activity (POF2-89571)$$cPOF2-89571$$fPOF II T$$x4
000154644 7001_ $$0P:(DE-Juel1)144807$$aDenker, Michael$$b1
000154644 7001_ $$0P:(DE-HGF)0$$aStoewer, Adrian$$b2
000154644 7001_ $$0P:(DE-HGF)0$$aJaillet, Florent$$b3
000154644 7001_ $$0P:(DE-HGF)0$$aBrochier, Thomas$$b4
000154644 7001_ $$0P:(DE-HGF)0$$aRiehle, Alexa$$b5
000154644 7001_ $$0P:(DE-HGF)0$$aWachtler, Thomas$$b6
000154644 7001_ $$0P:(DE-Juel1)144168$$aGrün, Sonja$$b7
000154644 773__ $$y2014
000154644 909CO $$ooai:juser.fz-juelich.de:154644$$popenaire$$pec_fundedresources$$pVDB
000154644 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)145394$$aForschungszentrum Jülich GmbH$$b0$$kFZJ
000154644 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)144807$$aForschungszentrum Jülich GmbH$$b1$$kFZJ
000154644 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)144168$$aForschungszentrum Jülich GmbH$$b7$$kFZJ
000154644 9132_ $$0G:(DE-HGF)POF3-571$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vConnectivity and Activity$$x0
000154644 9131_ $$0G:(DE-HGF)POF2-331$$1G:(DE-HGF)POF2-330$$2G:(DE-HGF)POF2-300$$3G:(DE-HGF)POF2$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lFunktion und Dysfunktion des Nervensystems$$vSignalling Pathways and Mechanisms in the Nervous System$$x0
000154644 9131_ $$0G:(DE-HGF)POF2-89571$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vConnectivity and Activity$$x1
000154644 9141_ $$y2014
000154644 9201_ $$0I:(DE-Juel1)INM-6-20090406$$kINM-6$$lComputational and Systems Neuroscience$$x0
000154644 9201_ $$0I:(DE-Juel1)IAS-6-20130828$$kIAS-6$$lTheoretical Neuroscience$$x1
000154644 980__ $$aabstract
000154644 980__ $$aVDB
000154644 980__ $$aI:(DE-Juel1)INM-6-20090406
000154644 980__ $$aI:(DE-Juel1)IAS-6-20130828
000154644 980__ $$aUNRESTRICTED
000154644 981__ $$aI:(DE-Juel1)IAS-6-20130828
000154644 981__ $$aI:(DE-Juel1)IAS-6-20130828