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000015476 0247_ $$2DOI$$a10.1088/0953-8984/23/18/184117
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000015476 084__ $$2WoS$$aPhysics, Condensed Matter
000015476 1001_ $$0P:(DE-Juel1)VDB71679$$aChelakkot, R.$$b0$$uFZJ
000015476 245__ $$aSemiflexible polymer conformation, distribution and migration in microcapillary flows
000015476 260__ $$aBristol$$bIOP Publ.$$c2011
000015476 300__ $$a184117
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000015476 440_0 $$03703$$aJournal of Physics: Condensed Matter$$v23$$x0953-8984$$y18
000015476 500__ $$aThe financial support and the stimulating environment of the DFG priority program 'Nano- and Microfluidics' is gratefully acknowledged. In particular, we thank R Finken and U Seifert (Stuttgart), L Schmid and T Franke (Augsburg), and D Steinhauser and T Pfohl (Gottingen and Basel) for many helpful and inspiring discussions.
000015476 520__ $$aThe flow behavior of a semiflexible polymer in microchannels is studied using multiparticle collision dynamics, a particle-based hydrodynamic simulation technique. Conformations, distributions, and radial cross-streamline migration are investigated for various bending rigidities, with persistence lengths L(p) in the range 0.5 ≤ L(p)/L(r) ≤ 30. The flow behavior is governed by the competition between a hydrodynamic lift force and steric repulsion from the wall, which lead to migration away from the wall, and a locally varying flow induced orientation, which drives the polymer away from the channel center and towards the wall. The different dependences of these effects on the polymer bending rigidity and the flow velocity results in a complex dynamical behavior. However, a generic effect is the appearance of a maximum in the monomer and the center-of-mass distributions, which occurs at the channel center for small flow velocities, but moves off-center at higher velocities.
000015476 536__ $$0G:(DE-Juel1)FUEK505$$2G:(DE-HGF)$$aBioSoft: Makromolekulare Systeme und biologische Informationsverarbeitung$$cP45$$x0
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000015476 650_2 $$2MeSH$$aAlgorithms
000015476 650_2 $$2MeSH$$aAnimals
000015476 650_2 $$2MeSH$$aBiophysics: methods
000015476 650_2 $$2MeSH$$aComputer Simulation
000015476 650_2 $$2MeSH$$aDiffusion
000015476 650_2 $$2MeSH$$aErythrocytes: cytology
000015476 650_2 $$2MeSH$$aHumans
000015476 650_2 $$2MeSH$$aHydrodynamics
000015476 650_2 $$2MeSH$$aModels, Chemical
000015476 650_2 $$2MeSH$$aMolecular Conformation
000015476 650_2 $$2MeSH$$aMotion
000015476 650_2 $$2MeSH$$aNanotechnology: methods
000015476 650_2 $$2MeSH$$aPolymers: chemistry
000015476 650_2 $$2MeSH$$aSolvents: chemistry
000015476 650_7 $$00$$2NLM Chemicals$$aPolymers
000015476 650_7 $$00$$2NLM Chemicals$$aSolvents
000015476 650_7 $$2WoSType$$aJ
000015476 7001_ $$0P:(DE-Juel1)131039$$aWinkler, R.G.$$b1$$uFZJ
000015476 7001_ $$0P:(DE-Juel1)130665$$aGompper, G.$$b2$$uFZJ
000015476 773__ $$0PERI:(DE-600)1472968-4$$a10.1088/0953-8984/23/18/184117$$gVol. 23, p. 184117$$p184117$$q23<184117$$tJournal of physics / Condensed matter$$v23$$x0953-8984$$y2011
000015476 8567_ $$uhttp://dx.doi.org/10.1088/0953-8984/23/18/184117
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