%0 Journal Article
%A Ermert, Johannes
%T 18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
%J BioMed research international
%V 2014
%N ID 812973
%@ 2314-6141
%C New York [u.a.]
%I Hindawi
%M FZJ-2014-04138
%P 1 - 15
%D 2014
%X This brief review gives an overview of newer developments in 18F-chemistry with the focus on small 18F-labelled molecules as intermediates for modular build-up syntheses. The short half-life (<2 h) of the radionuclide requires efficient syntheses of these intermediates considering that multistep syntheses are often time consuming and characterized by a loss of yield in each reaction step. Recent examples of improved synthesis of 18F-labelled intermediates show new possibilities for no-carrier-added ring-fluorinated arenes, novel intermediates for tri[18F]fluoromethylation reactions, and 18F-fluorovinylation methods
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000341881700001
%R 10.1155/2014/812973
%U https://juser.fz-juelich.de/record/154927