TY  - JOUR
AU  - Ermert, Johannes
TI  - 18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments
JO  - BioMed research international
VL  - 2014
IS  - ID 812973
SN  - 2314-6141
CY  - New York [u.a.]
PB  - Hindawi
M1  - FZJ-2014-04138
SP  - 1 - 15
PY  - 2014
AB  - This brief review gives an overview of newer developments in 18F-chemistry with the focus on small 18F-labelled molecules as intermediates for modular build-up syntheses. The short half-life (<2 h) of the radionuclide requires efficient syntheses of these intermediates considering that multistep syntheses are often time consuming and characterized by a loss of yield in each reaction step. Recent examples of improved synthesis of 18F-labelled intermediates show new possibilities for no-carrier-added ring-fluorinated arenes, novel intermediates for tri[18F]fluoromethylation reactions, and 18F-fluorovinylation methods
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000341881700001
DO  - DOI:10.1155/2014/812973
UR  - https://juser.fz-juelich.de/record/154927
ER  -