000155133 001__ 155133 000155133 005__ 20240313095017.0 000155133 020__ $$a978-3-319-12083-6 (print) 000155133 020__ $$a978-3-319-12084-3 (electronic) 000155133 0247_ $$2doi$$a10.1007/978-3-319-12084-3_3 000155133 0247_ $$2ISSN$$a0302-9743 000155133 0247_ $$2ISSN$$a1611-3349 000155133 0247_ $$2WOS$$aWOS:000345024600003 000155133 037__ $$aFZJ-2014-04318 000155133 082__ $$a004 000155133 1001_ $$0P:(DE-Juel1)138512$$avan Albada, Sacha$$b0$$eCorresponding Author$$ufzj 000155133 1112_ $$a1st International Workshop on Brain-inspired Computing$$cCetraro$$d2013-07-08 - 2013-07-11$$gBrainComp 2013$$wItaly 000155133 245__ $$aIntegrating brain structure and dynamics on supercomputers 000155133 260__ $$aCham Heidelberg New York Dordrecht London$$bSpringer$$c2014 000155133 29510 $$aBrain-inspired Computing 000155133 300__ $$a22-32 000155133 3367_ $$2ORCID$$aCONFERENCE_PAPER 000155133 3367_ $$033$$2EndNote$$aConference Paper 000155133 3367_ $$2BibTeX$$aINPROCEEDINGS 000155133 3367_ $$2DRIVER$$aconferenceObject 000155133 3367_ $$2DataCite$$aOutput Types/Conference Paper 000155133 3367_ $$0PUB:(DE-HGF)8$$2PUB:(DE-HGF)$$aContribution to a conference proceedings$$bcontrib$$mcontrib$$s1563263897_1091 000155133 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$mcontb 000155133 4900_ $$aLecture Notes in Computer Science$$v8603 000155133 500__ $$aDOI: 10.1007/978-3-319-12084-3_3 000155133 520__ $$aLarge-scale simulations of neuronal networks provide a unique view onto brain dynamics, complementing experiments, small-scale simulations, and theory. They enable the investigation of integrative models to arrive at a multi-scale picture of brain dynamics relating macroscopic imaging measures to the microscopic dynamics. Recent years have seen rapid development of the necessary simulation technology. We give an overview of design features of the NEural Simulation Tool (NEST) that enable simulations of spiking point neurons to be scaled to hundreds of thousands of processors. The performance of supercomputing applications is traditionally assessed using scalability plots. We discuss reasons why such measures should be interpreted with care in the context of neural network simulations. The scalability of neural network simulations on available supercomputers is limited by memory constraints rather than computational speed. 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