% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Kirchenbuechler:156365,
      author       = {Kirchenbuechler, Inka and Guu, Donald and Kurniawan,
                      Nicholas A. and Koenderink, Gijsje H. and Lettinga, M.P.},
      title        = {{D}irect visualization of flow-induced conformational
                      transitions of single actin filaments in entangled
                      solutions},
      journal      = {Nature Communications},
      volume       = {5},
      issn         = {2041-1723},
      address      = {London},
      publisher    = {Nature Publishing Group},
      reportid     = {FZJ-2014-05117},
      pages        = {5060},
      year         = {2014},
      abstract     = {While semi-flexible polymers and fibres are an important
                      class of material due to their rich mechanical properties,
                      it remains unclear how these properties relate to the
                      microscopic conformation of the polymers. Actin filaments
                      constitute an ideal model polymer system due to their
                      micron-sized length and relatively high stiffness that allow
                      imaging at the single filament level. Here we study the
                      effect of entanglements on the conformational dynamics of
                      actin filaments in shear flow. We directly measure the full
                      three-dimensional conformation of single actin filaments,
                      using confocal microscopy in combination with a
                      counter-rotating cone-plate shear cell. We show that
                      initially entangled filaments form disentangled
                      orientationally ordered hairpins, confined in the
                      flow-vorticity plane. In addition, shear flow causes
                      stretching and shear alignment of the hairpin tails, while
                      the filament length distribution remains unchanged. These
                      observations explain the strain-softening and shear-thinning
                      behaviour of entangled F-actin solutions, which aids the
                      understanding of the flow behaviour of complex fluids
                      containing semi-flexible polymers.},
      cin          = {ICS-7 / ICS-3},
      ddc          = {500},
      cid          = {I:(DE-Juel1)ICS-7-20110106 / I:(DE-Juel1)ICS-3-20110106},
      pnm          = {453 - Physics of the Cell (POF2-453)},
      pid          = {G:(DE-HGF)POF2-453},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000343976900003},
      pubmed       = {pmid:25297898},
      doi          = {10.1038/ncomms6060},
      url          = {https://juser.fz-juelich.de/record/156365},
}