000015773 001__ 15773 000015773 005__ 20190625110743.0 000015773 0247_ $$2pmid$$apmid:21725038 000015773 0247_ $$2pmc$$apmc:PMC3450920 000015773 0247_ $$2DOI$$a10.1093/cercor/bhr166 000015773 0247_ $$2WOS$$aWOS:000302004600020 000015773 0247_ $$2altmetric$$aaltmetric:181461 000015773 037__ $$aPreJuSER-15773 000015773 041__ $$aeng 000015773 082__ $$a610 000015773 1001_ $$0P:(DE-Juel1)136848$$aBzdok, D.$$b0$$uFZJ 000015773 245__ $$aThe Modular Neuroarchitecture of Social Judgments on Faces 000015773 260__ $$aOxford$$bOxford Univ. Press$$c2012 000015773 300__ $$a951-961 000015773 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article 000015773 3367_ $$2DataCite$$aOutput Types/Journal article 000015773 3367_ $$00$$2EndNote$$aJournal Article 000015773 3367_ $$2BibTeX$$aARTICLE 000015773 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000015773 3367_ $$2DRIVER$$aarticle 000015773 440_0 $$01171$$aCerebral Cortex$$x1047-3211 000015773 500__ $$3POF3_Assignment on 2016-02-29 000015773 500__ $$aRecord converted from VDB: 12.11.2012 000015773 520__ $$aFace-derived information on trustworthiness and attractiveness crucially influences social interaction. It is, however, unclear to what degree the functional neuroanatomy of these complex social judgments on faces reflects genuine social versus basic emotional and cognitive processing. To disentangle social from nonsocial contributions, we assessed commonalities and differences between the functional networks activated by judging social (trustworthiness, attractiveness), emotional (happiness), and cognitive (age) facial traits. Relative to happiness and age evaluations, both trustworthiness and attractiveness judgments selectively activated the dorsomedial prefrontal cortex and inferior frontal gyrus, forming a core social cognition network. Moreover, they also elicited a higher amygdalar response than even the emotional control condition. Both social judgments differed, however, in their top-down modulation of face-sensitive regions: trustworthiness judgments recruited the posterior superior temporal sulcus, whereas attractiveness judgments recruited the fusiform gyrus. Social and emotional judgments converged and, therefore, likely interact in the ventromedial prefrontal cortex. Social and age judgments, on the other hand, commonly engaged the anterior insula, inferior parietal cortex, and dorsolateral prefrontal cortex, which appear to subserve more cognitive aspects in social evaluation. These findings demonstrate the modularity of social judgments on human faces by separating the neural correlates of social, face-specific, emotional, and cognitive processing facets. 000015773 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems$$cP33$$x0 000015773 588__ $$aDataset connected to Pubmed 000015773 650_2 $$2MeSH$$aAdult 000015773 650_2 $$2MeSH$$aAnalysis of Variance 000015773 650_2 $$2MeSH$$aBrain: blood supply 000015773 650_2 $$2MeSH$$aBrain: physiology 000015773 650_2 $$2MeSH$$aBrain Mapping 000015773 650_2 $$2MeSH$$aCognition: physiology 000015773 650_2 $$2MeSH$$aEmotions: physiology 000015773 650_2 $$2MeSH$$aFace 000015773 650_2 $$2MeSH$$aFemale 000015773 650_2 $$2MeSH$$aHumans 000015773 650_2 $$2MeSH$$aImage Processing, Computer-Assisted 000015773 650_2 $$2MeSH$$aJudgment: physiology 000015773 650_2 $$2MeSH$$aLikelihood Functions 000015773 650_2 $$2MeSH$$aMagnetic Resonance Imaging 000015773 650_2 $$2MeSH$$aMale 000015773 650_2 $$2MeSH$$aMiddle Aged 000015773 650_2 $$2MeSH$$aOxygen: blood 000015773 650_2 $$2MeSH$$aPattern Recognition, Visual: physiology 000015773 650_2 $$2MeSH$$aPhotic Stimulation 000015773 650_2 $$2MeSH$$aReaction Time: physiology 000015773 650_2 $$2MeSH$$aSocial Perception 000015773 650_2 $$2MeSH$$aStatistics as Topic 000015773 650_2 $$2MeSH$$aYoung Adult 000015773 650_7 $$07782-44-7$$2NLM Chemicals$$aOxygen 000015773 7001_ $$0P:(DE-Juel1)131693$$aLangner, R.$$b1$$uFZJ 000015773 7001_ $$0P:(DE-Juel1)131684$$aHoffstaedter, F.$$b2$$uFZJ 000015773 7001_ $$0P:(DE-HGF)0$$aTuretsky, B.I.$$b3 000015773 7001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b4$$uFZJ 000015773 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, S.B.$$b5$$uFZJ 000015773 773__ $$0PERI:(DE-600)1483485-6$$a10.1093/cercor/bhr166$$n4$$p951-961$$tCerebral cortex$$v22$$x1047-3211$$y2012 000015773 8567_ $$2Pubmed Central$$uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3450920 000015773 909CO $$ooai:juser.fz-juelich.de:15773$$pVDB 000015773 915__ $$0StatID:(DE-HGF)0010$$2StatID$$aJCR/ISI refereed 000015773 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR 000015773 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index 000015773 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000015773 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000015773 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000015773 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000015773 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000015773 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000015773 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG 000015773 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz 000015773 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences 000015773 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews 000015773 9141_ $$y2012 000015773 9131_ $$0G:(DE-Juel1)FUEK409$$bGesundheit$$kP33$$lFunktion und Dysfunktion des Nervensystems$$vFunktion und Dysfunktion des Nervensystems$$x0 000015773 9132_ $$0G:(DE-HGF)POF3-579H$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vAddenda$$x0 000015773 9201_ $$0I:(DE-Juel1)INM-2-20090406$$gINM$$kINM-2$$lMolekulare Organisation des Gehirns$$x0 000015773 970__ $$aVDB:(DE-Juel1)129071 000015773 980__ $$aVDB 000015773 980__ $$aConvertedRecord 000015773 980__ $$ajournal 000015773 980__ $$aI:(DE-Juel1)INM-2-20090406 000015773 980__ $$aUNRESTRICTED