TY  - JOUR
AU  - Dippel, A.-C.
AU  - Schneller, T.
AU  - Dornseiffer, J.
AU  - Waser, R.
TI  - PbTiO3 nanoparticle precursors for chemical solution deposited electroceramic thin films
JO  - Journal of sol gel science and technology
VL  - 57
SN  - 0928-0707
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V
M1  - PreJuSER-16901
SP  - 36 - 42
PY  - 2011
N1  - Record converted from VDB: 12.11.2012
AB  - The Vascular Registry (VR) on carotid procedures collects long-term outcomes on carotid artery stenting (CAS) and carotid endarterectomy (CEA) patients. The purpose of this report is to describe in-hospital and 30-day CAS outcomes in patients with atherosclerotic carotid artery disease (CAD; atherosclerosis [ATH]) compared to recurrent carotid stenosis (RES) and radiation-induced stenosis (RAD).The VR collects provider-reported data on CAS using a Web-based data management system. For this report, data were analyzed at the preprocedure, procedure, predischarge, and 30-day intervals.As of November 20, 2008, there were 4017 patients with CAS with discharge data, of which 72% were due to ATH. A total of 2321 patients were available for 30-day outcomes analysis (1623 ATH, 529 restenosis, 119 radiation, 17 dissection, 3 trauma, and 30 other). Baseline demographics showed that ATH occurred in older patients (72-years-old), had the greatest history of coronary artery disease (CAD; 62%), myocardial infarction (MI; 24%), valvular heart disease (8%), arrhythmia (16%), congestive heart failure (CHF; 16%), diabetes mellitus (DM; 35%), and chronic obstructive pulmonary disease (COPD; 20%). RES had a higher degree of baseline stenosis (87.0 vs 85.8 ATH; P = .010), were less likely to be symptomatic (35.5% vs 46.3% ATH; P < .001), but had a greater history of hypertension, peripheral vascular disease (PVD), and smoking. RAD was seen in younger patients (66.6 vs 71.7 ATH; P < .001), were more likely to be male (78.2% vs 60.9% ATH; P < .001), and had less comorbidities overall, with the exception of amaurosis fugax, smoking, and cancer. The only statistically significant difference in perioperative rates was in transient ischemic attack (TIA; 2.7% ATH vs 0.9% RES; P = .02). There were no statistically significant differences in in-hospital death/stroke/MI (ATH 5.4%, RES 3.8%, RAD 4.2%) or at 30 days (ATH 7.1%, RES 5.1%, RAD 5.0%). Even after adjusting for age, gender, symptomatology, CHF, and renal failure, the only statistically significant difference at 30 days was amaurosis fugax between ATH and RAD (odds ratio [OR] 0.13; P = .01).Although patients with ATH have statistically significant comorbidities, they did not have statistically significant increased rates of death/stroke/MI during hospitalization or within 30 days after discharge when compared to RES or RAD. The CAS event rates for ATH vs RES and RAD are similar, despite prior published reports. Symptomatic ATH have statistically significant higher rates of death/stroke/MI compared to asymptomatic cohort. Finally, consistent and accurate entry of long-term data beyond initial hospitalization is essential to fully assess CAS outcomes since a significant number of adverse events occur in the interval from hospital discharge to 30 days.
KW  - Aged
KW  - Aged, 80 and over
KW  - Analysis of Variance
KW  - Angioplasty: instrumentation
KW  - Angioplasty: methods
KW  - Angioplasty: mortality
KW  - Atherosclerosis: pathology
KW  - Atherosclerosis: surgery
KW  - Atherosclerosis: ultrasonography
KW  - Carotid Stenosis: mortality
KW  - Carotid Stenosis: pathology
KW  - Carotid Stenosis: surgery
KW  - Carotid Stenosis: ultrasonography
KW  - Cohort Studies
KW  - Endarterectomy, Carotid: adverse effects
KW  - Endarterectomy, Carotid: methods
KW  - Female
KW  - Hospital Mortality: trends
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Odds Ratio
KW  - Postoperative Complications: epidemiology
KW  - Postoperative Complications: physiopathology
KW  - Probability
KW  - Prosthesis Failure
KW  - Registries
KW  - Risk Assessment
KW  - Severity of Illness Index
KW  - Societies, Medical
KW  - Stents
KW  - Survival Analysis
KW  - Ultrasonography, Doppler, Duplex
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:20347551
UR  - <Go to ISI:>//WOS:000285974700008
DO  - DOI:10.1007/s10971-010-2321-7
UR  - https://juser.fz-juelich.de/record/16901
ER  -