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| 001 | 16983 | ||
| 005 | 20240610120557.0 | ||
| 024 | 7 | _ | |2 DOI |a 10.1039/C1SM05794D |
| 024 | 7 | _ | |2 WOS |a WOS:000296388300060 |
| 024 | 7 | _ | |2 Handle |a 2128/7336 |
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| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 530 |
| 084 | _ | _ | |2 WoS |a Chemistry, Physical |
| 084 | _ | _ | |2 WoS |a Materials Science, Multidisciplinary |
| 084 | _ | _ | |2 WoS |a Physics, Multidisciplinary |
| 084 | _ | _ | |2 WoS |a Polymer Science |
| 100 | 1 | _ | |0 P:(DE-Juel1)VDB96421 |a McWhirter, J.L. |b 0 |u FZJ |
| 245 | _ | _ | |a Deformation and clustering of red blood cells in microcapillary flows |
| 260 | _ | _ | |a Cambridge |b Royal Society of Chemistry (RSC) |c 2011 |
| 300 | _ | _ | |a 10967 - 10977 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
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| 440 | _ | 0 | |0 16881 |a Soft Matter |v 7 |x 1744-683X |y 22 |
| 500 | _ | _ | |a We thank I. O. Gotze, T. Auth, M. Ripoll, G. Vliegenthart, and R. G. Winkler for helpful discussions. Support of this work by the DFG through the priority program SPP1164, 'Nano- and Microfluidics', is gratefully acknowledged. |
| 520 | _ | _ | |a The shape changes and clustering of red blood cells (RBCs) under flow in cylindrical microcapillaries are studied using a triangulated surface model for the membrane and a particle-based mesoscopic simulation technique for the embedding fluid. As the flow velocity increases, the RBCs make a transition from a discocyte shape at low velocities to a parachute shape at high velocities; close to the critical flow velocity, the RBC can also be found in a transient slipper shape. The transition and critical flow velocity are examined for various capillary diameters and RBC volume fractions (hematocrit H-T). At high flow velocities and low hematocrits, the parachute-shaped RBCs can be found in clusters which are hydrodynamically stabilized. Here, the formation of a fluid vortex between neighboring cells, called bolus, develops which keeps the cells at a preferred distance. Decreasing the flow velocity towards the critical velocity, we observe an increasing frequency of drastic RBC shape fluctuations to slipper-shaped RBCs that can result in cluster breakup. These clusters resemble those seen in experiments using optical microscopy. |
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| 773 | _ | _ | |0 PERI:(DE-600)2191476-X |a 10.1039/c1sm05794d |g Vol. 7, p. 10967 - 10977 |p 10967 - 10977 |q 7<10967 - 10977 |t Soft matter |v 7 |x 1744-683X |y 2011 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1039/C1SM05794D |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/16983/files/FZJ-16983.pdf |y Published under German "Allianz" Licensing conditions on 2011-09-23. Available in OpenAccess from 2012-09-23 |z Published final document. |
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