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@ARTICLE{Moschen:17017,
      author       = {Moschen, R. and Kühl, N. and Peters, S. and Vos, H. and
                      Lücke, A.},
      title        = {{T}emperature variability at {D}ürres {M}aar, {G}ermany,
                      during the {M}igration {P}eriod and at {H}igh {M}edieval
                      {T}imes, inferred from stable carbon isotopes of {S}phagnum
                      cellulose},
      journal      = {Climate of the past},
      volume       = {7},
      issn         = {1814-9332},
      address      = {Katlenburg-Lindau},
      publisher    = {Copernicus Ges.},
      reportid     = {PreJuSER-17017},
      pages        = {1011 - 1026},
      year         = {2011},
      note         = {We thank Georg Heumann, Thomas Litt, Jorn Parplies and Nils
                      Riedel for assistance in the field. The help of Stefanie
                      Wagner during core sampling is greatly acknowledged. Stable
                      isotope measurements were carried out by Holger Wissel at
                      the Institute of Bio- and Geosciences, Agrosphere. This work
                      was supported by a grant of the Deutsche
                      Forschungsgemeinschaft (German Research Foundation) to
                      Robert Moschen (grant MO 1401/2-2).},
      abstract     = {To assess the risk and identify risk factors of Hodgkin
                      lymphoma (HL) in solid organ transplant recipients. Prior
                      research has been limited by the rarity of HL and the
                      requirement for extended follow-up after
                      transplantation.Using data from the Scientific Registry of
                      Transplant Recipients (SRTR), we conducted a retrospective
                      cohort study of US solid organ transplant recipients
                      (1997-2007). We estimated hazard ratios (HRs) for HL risk
                      factors using proportional hazards regression. Standardized
                      incidence ratios (SIRs) compared HL risk in the transplant
                      cohort with the general population.The cohort included
                      283,190 transplant recipients (average follow-up: 3.7 years
                      after transplantation). Based on 73 cases, HL risk factors
                      included male gender (HR: 2.1, $95\%$ CI: 1.2-3.7), young
                      age (4.0, 2.3-6.8), and Epstein-Barr virus (EBV)
                      seronegativity at the time of transplantation (3.1,
                      1.2-8.1). Among tumors with EBV status information, $79\%$
                      were EBV positive, including all tumors in recipients who
                      were initially seronegative. Overall, HL risk was higher
                      than in the general population (SIR: 2.2) and increased
                      monotonically over time after transplantation (SIR: 4.1 at
                      8-10 years posttransplant). Excess HL risk was especially
                      high after heart and/or lung transplantation (SIR: 3.2).HL
                      is a late complication of solid organ transplantation. The
                      high HL risk in recipients who were young or EBV
                      seronegative at the time of transplant and the fact that
                      most HL tumors were EBV positive highlight the role of
                      primary EBV infection and poor immune control of this virus.
                      The occurrence of HL may rise with improved long-term
                      survival in transplant recipients.},
      keywords     = {Adolescent / Adult / Child / Cohort Studies / Female /
                      Follow-Up Studies / Hodgkin Disease: epidemiology / Humans /
                      Incidence / Male / Middle Aged / Organ Transplantation:
                      adverse effects / Proportional Hazards Models /
                      Retrospective Studies / Risk Factors / Time Factors / United
                      States / J (WoSType)},
      cin          = {IBG-3 / IEK-7},
      ddc          = {550},
      cid          = {I:(DE-Juel1)IBG-3-20101118 / I:(DE-Juel1)IEK-7-20101013},
      pnm          = {Terrestrische Umwelt / Atmosphäre und Klima / Erneuerbare
                      Energien},
      pid          = {G:(DE-Juel1)FUEK407 / G:(DE-Juel1)FUEK491 /
                      G:(DE-Juel1)FUEK401},
      shelfmark    = {Geosciences, Multidisciplinary / Meteorology $\&$
                      Atmospheric Sciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:20733533},
      pmc          = {pmc:PMC2967618},
      UT           = {WOS:000295356800023},
      doi          = {10.5194/cp-7-1011-2011},
      url          = {https://juser.fz-juelich.de/record/17017},
}