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@ARTICLE{Eickhoff:171837,
      author       = {Eickhoff, Simon and Laird, Angela R and Fox, Peter T and
                      Bzdok, Danilo and Hensel, Lukas},
      title        = {{F}unctional {S}egregation of the {H}uman {D}orsomedial
                      {P}refrontal {C}ortex.},
      journal      = {Cerebral cortex},
      volume       = {26},
      number       = {1},
      issn         = {1460-2199},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {FZJ-2014-05394},
      pages        = {304-321},
      year         = {2016},
      abstract     = {The human dorsomedial prefrontal cortex (dmPFC) has been
                      implicated in various complex cognitive processes, including
                      social cognition. To unravel its functional organization, we
                      assessed the dmPFC's regional heterogeneity, connectivity
                      patterns, and functional profiles. First, the heterogeneity
                      of a dmPFC seed, engaged during social processing, was
                      investigated by assessing local differences in whole-brain
                      coactivation profiles. Second, functional connectivity of
                      the ensuing dmPFC clusters was compared by task-constrained
                      meta-analytic coactivation mapping and task-unconstrained
                      resting-state correlations. Third, dmPFC clusters were
                      functionally profiled by forward/reverse inference. The
                      dmPFC seed was thus segregated into 4 clusters
                      (rostroventral, rostrodorsal, caudal-right, and
                      caudal-left). Both rostral clusters were connected to the
                      amygdala and hippocampus and associated with memory and
                      social cognitive tasks in functional decoding. The
                      rostroventral cluster exhibited strongest connectivity to
                      the default mode network. Unlike the rostral segregation,
                      the caudal dmPFC was divided by hemispheres. The
                      caudal-right cluster was strongly connected to a
                      frontoparietal network (dorsal attention network), whereas
                      the caudal-left cluster was strongly connected to the
                      anterior midcingulate cortex and bilateral anterior insula
                      (salience network). In conclusion, we demonstrate that a
                      dmPFC seed reflecting social processing can be divided into
                      4 separate functional modules that contribute to distinct
                      facets of advanced human cognition.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {333 - Pathophysiological Mechanisms of Neurological and
                      Psychiatric Diseases (POF2-333)},
      pid          = {G:(DE-HGF)POF2-333},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:25331597},
      UT           = {WOS:000370972500029},
      doi          = {10.1093/cercor/bhu250},
      url          = {https://juser.fz-juelich.de/record/171837},
}