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@ARTICLE{TiruttaniSubhramanyam:172418,
      author       = {Tiruttani Subhramanyam, Udaya Kumar and Kubicek, Jan and
                      Eidhoff, Ulf B. and Labahn, Jörg},
      title        = {{C}loning, expression, purification, crystallization and
                      preliminary crystallographic analysis of the {C}-terminal
                      domain of {P}ar-4 ({PAWR})},
      journal      = {Acta crystallographica / F},
      volume       = {70},
      issn         = {1744-3091},
      address      = {Oxford [u.a.]},
      publisher    = {Blackwell},
      reportid     = {FZJ-2014-05896},
      pages        = {1224 - 1227},
      year         = {2014},
      abstract     = {Prostate apoptosis response-4 protein is an intrinsically
                      disordered pro-apoptotic protein with tumour suppressor
                      function. Par-4 is known for its selective induction of
                      apoptosis in cancer cells only and its ability to interact
                      with various apoptotic proteins via its C-terminus. Par-4,
                      with its unique function and various interacting partners,
                      has gained importance as a potential target for cancer
                      therapy. The C-terminus of the rat homologue of Par-4 was
                      crystallized and a 3.7 Å resolution X-ray diffraction
                      data set was collected. Preliminary data analysis shows the
                      space group to be P41212. The unit-cell parameters are a = b
                      = 115.351, c = 123.663 Å, α = β = γ = 90°.},
      cin          = {ICS-6},
      ddc          = {530},
      cid          = {I:(DE-Juel1)ICS-6-20110106},
      pnm          = {452 - Structural Biology (POF2-452)},
      pid          = {G:(DE-HGF)POF2-452},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000341818600019},
      pubmed       = {pmid:25195896},
      doi          = {10.1107/S2053230X14014691},
      url          = {https://juser.fz-juelich.de/record/172418},
}