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000017302 0247_ $$2DOI$$a10.1190/1.3575285
000017302 0247_ $$2ISSN$$a1070-485X
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000017302 041__ $$aeng
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000017302 1001_ $$0P:(DE-HGF)0$$aBeasley, C.J.$$b0
000017302 245__ $$aIntroduction to this special section: Geoscientists Without Borders
000017302 260__ $$aTulsa, Okla.$$bSociety of Exploration Geophysicists$$c2011
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000017302 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000017302 440_0 $$023363$$aThe Leading Edge$$v30$$x1070-485X$$y4
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000017302 520__ $$aTo determine the prevalence of conjunctivochalasis in patients with immune thyroid diseases, to determine whether there is any association between the 2 diseases, and to determine cytologic study of conjunctivochalasis through the cytology impression test.A clinical prospective cohort study carried out by the External Diseases Department in the Ophthalmology Sector and the Thyroid Department in the Endocrinology Sector at Federal University of Sao Paulo (UNIFESP). The patients included were divided into 2 groups following these inclusion criteria: a control group of 25 patients without thyroid diseases, confirmed after clinical and laboratory examinations (thyroid hormones), or any other ocular diseases. The study group consisted of 31 patients with thyroid diseases, the diagnosis of which was confirmed by the Endocrinology Sector. The thyroidopathies included were autoimmune diseases but excluded nonautoimmune diseases. A protocol endorsed by the UNIFESP was followed, using clinical and ophthalmological history, biomicroscopy, and impression cytology.Fifty-two percent of patients without thyroid diseases and 88% of patients with thyroid diseases presented with conjunctivochalasis. The risk ratio was 1.705 (Pr > chi(2) = 0.0038), indicating that there is an association between them. For the impression cytology in inferior bulbar conjunctiva, there was an association between the result of the impression cytology and conjunctivochalasis (Pearson chi(2) = 10.1190 Pr = 0.006).The prevalence of conjunctivochalasis in patients with autoimmune thyroid diseases was 88%. Patients with autoimmune thyroidopathy presented higher percentages of conjunctivochalasis than the control group, confirming the association between them. The cytologic study showed the highest prevalence of abnormal surface features in eyes with conjunctivochalasis.
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000017302 650_2 $$2MeSH$$aAdult
000017302 650_2 $$2MeSH$$aAged
000017302 650_2 $$2MeSH$$aConjunctiva: pathology
000017302 650_2 $$2MeSH$$aDiagnosis, Differential
000017302 650_2 $$2MeSH$$aFollow-Up Studies
000017302 650_2 $$2MeSH$$aHumans
000017302 650_2 $$2MeSH$$aKeratoconjunctivitis Sicca: epidemiology
000017302 650_2 $$2MeSH$$aKeratoconjunctivitis Sicca: etiology
000017302 650_2 $$2MeSH$$aKeratoconjunctivitis Sicca: pathology
000017302 650_2 $$2MeSH$$aMiddle Aged
000017302 650_2 $$2MeSH$$aPrevalence
000017302 650_2 $$2MeSH$$aProspective Studies
000017302 650_2 $$2MeSH$$aSeverity of Illness Index
000017302 650_2 $$2MeSH$$aThyroiditis, Autoimmune: complications
000017302 650_2 $$2MeSH$$aThyroiditis, Autoimmune: pathology
000017302 7001_ $$0P:(DE-HGF)0$$aPellerin, L.$$b1
000017302 7001_ $$0P:(DE-Juel1)129561$$avan der Kruk, J.$$b2$$uFZJ
000017302 7001_ $$0P:(DE-Juel1)VDB102019$$aJacobs, R.$$b3$$uFZJ
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000017302 8567_ $$uhttp://dx.doi.org/10.1190/1.3575285
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000017302 9141_ $$y2011
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