TY  - JOUR
AU  - Beasley, C.J.
AU  - Pellerin, L.
AU  - van der Kruk, J.
AU  - Jacobs, R.
TI  - Introduction to this special section: Geoscientists Without Borders
JO  - The Leading Edge
VL  - 30
SN  - 1070-485X
CY  - Tulsa, Okla.
PB  - Society of Exploration Geophysicists
M1  - PreJuSER-17302
SP  - 400
PY  - 2011
N1  - Record converted from VDB: 12.11.2012
AB  - To determine the prevalence of conjunctivochalasis in patients with immune thyroid diseases, to determine whether there is any association between the 2 diseases, and to determine cytologic study of conjunctivochalasis through the cytology impression test.A clinical prospective cohort study carried out by the External Diseases Department in the Ophthalmology Sector and the Thyroid Department in the Endocrinology Sector at Federal University of Sao Paulo (UNIFESP). The patients included were divided into 2 groups following these inclusion criteria: a control group of 25 patients without thyroid diseases, confirmed after clinical and laboratory examinations (thyroid hormones), or any other ocular diseases. The study group consisted of 31 patients with thyroid diseases, the diagnosis of which was confirmed by the Endocrinology Sector. The thyroidopathies included were autoimmune diseases but excluded nonautoimmune diseases. A protocol endorsed by the UNIFESP was followed, using clinical and ophthalmological history, biomicroscopy, and impression cytology.Fifty-two percent of patients without thyroid diseases and 88% of patients with thyroid diseases presented with conjunctivochalasis. The risk ratio was 1.705 (Pr > chi(2) = 0.0038), indicating that there is an association between them. For the impression cytology in inferior bulbar conjunctiva, there was an association between the result of the impression cytology and conjunctivochalasis (Pearson chi(2) = 10.1190 Pr = 0.006).The prevalence of conjunctivochalasis in patients with autoimmune thyroid diseases was 88%. Patients with autoimmune thyroidopathy presented higher percentages of conjunctivochalasis than the control group, confirming the association between them. The cytologic study showed the highest prevalence of abnormal surface features in eyes with conjunctivochalasis.
KW  - Adult
KW  - Aged
KW  - Conjunctiva: pathology
KW  - Diagnosis, Differential
KW  - Follow-Up Studies
KW  - Humans
KW  - Keratoconjunctivitis Sicca: epidemiology
KW  - Keratoconjunctivitis Sicca: etiology
KW  - Keratoconjunctivitis Sicca: pathology
KW  - Middle Aged
KW  - Prevalence
KW  - Prospective Studies
KW  - Severity of Illness Index
KW  - Thyroiditis, Autoimmune: complications
KW  - Thyroiditis, Autoimmune: pathology
LB  - PUB:(DE-HGF)16
C6  - pmid:17068455
DO  - DOI:10.1190/1.3575285
UR  - https://juser.fz-juelich.de/record/17302
ER  -