001     17302
005     20180208233241.0
024 7 _ |2 pmid
|a pmid:17068455
024 7 _ |2 DOI
|a 10.1190/1.3575285
024 7 _ |2 ISSN
|a 1070-485X
037 _ _ |a PreJuSER-17302
041 _ _ |a eng
082 _ _ |a 550
100 1 _ |a Beasley, C.J.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Introduction to this special section: Geoscientists Without Borders
260 _ _ |c 2011
|a Tulsa, Okla.
|b Society of Exploration Geophysicists
300 _ _ |a 400
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
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336 7 _ |a Journal Article
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a article
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440 _ 0 |a The Leading Edge
|x 1070-485X
|0 23363
|y 4
|v 30
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520 _ _ |a To determine the prevalence of conjunctivochalasis in patients with immune thyroid diseases, to determine whether there is any association between the 2 diseases, and to determine cytologic study of conjunctivochalasis through the cytology impression test.A clinical prospective cohort study carried out by the External Diseases Department in the Ophthalmology Sector and the Thyroid Department in the Endocrinology Sector at Federal University of Sao Paulo (UNIFESP). The patients included were divided into 2 groups following these inclusion criteria: a control group of 25 patients without thyroid diseases, confirmed after clinical and laboratory examinations (thyroid hormones), or any other ocular diseases. The study group consisted of 31 patients with thyroid diseases, the diagnosis of which was confirmed by the Endocrinology Sector. The thyroidopathies included were autoimmune diseases but excluded nonautoimmune diseases. A protocol endorsed by the UNIFESP was followed, using clinical and ophthalmological history, biomicroscopy, and impression cytology.Fifty-two percent of patients without thyroid diseases and 88% of patients with thyroid diseases presented with conjunctivochalasis. The risk ratio was 1.705 (Pr > chi(2) = 0.0038), indicating that there is an association between them. For the impression cytology in inferior bulbar conjunctiva, there was an association between the result of the impression cytology and conjunctivochalasis (Pearson chi(2) = 10.1190 Pr = 0.006).The prevalence of conjunctivochalasis in patients with autoimmune thyroid diseases was 88%. Patients with autoimmune thyroidopathy presented higher percentages of conjunctivochalasis than the control group, confirming the association between them. The cytologic study showed the highest prevalence of abnormal surface features in eyes with conjunctivochalasis.
536 _ _ |a Terrestrische Umwelt
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650 _ 2 |2 MeSH
|a Adult
650 _ 2 |2 MeSH
|a Aged
650 _ 2 |2 MeSH
|a Conjunctiva: pathology
650 _ 2 |2 MeSH
|a Diagnosis, Differential
650 _ 2 |2 MeSH
|a Follow-Up Studies
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Keratoconjunctivitis Sicca: epidemiology
650 _ 2 |2 MeSH
|a Keratoconjunctivitis Sicca: etiology
650 _ 2 |2 MeSH
|a Keratoconjunctivitis Sicca: pathology
650 _ 2 |2 MeSH
|a Middle Aged
650 _ 2 |2 MeSH
|a Prevalence
650 _ 2 |2 MeSH
|a Prospective Studies
650 _ 2 |2 MeSH
|a Severity of Illness Index
650 _ 2 |2 MeSH
|a Thyroiditis, Autoimmune: complications
650 _ 2 |2 MeSH
|a Thyroiditis, Autoimmune: pathology
700 1 _ |a Pellerin, L.
|b 1
|0 P:(DE-HGF)0
700 1 _ |a van der Kruk, J.
|b 2
|u FZJ
|0 P:(DE-Juel1)129561
700 1 _ |a Jacobs, R.
|b 3
|u FZJ
|0 P:(DE-Juel1)VDB102019
773 _ _ |0 PERI:(DE-600)2083479-2
|a 10.1190/1.3575285
|g Vol. 30, p. 400
|p 400
|q 30<400
|t The Leading Edge
|v 30
|x 1070-485X
|y 2011
856 7 _ |u http://dx.doi.org/10.1190/1.3575285
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