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@ARTICLE{Abel:17374,
      author       = {Abel, S. and Huber, W. and Weiller, C. and Amunts, K. and
                      Eickhoff, S.B. and Heim, S.},
      title        = {{T}he influence of handedness on hemispheric interaction
                      during word production: {I}nsights form effective
                      connectivity analysis},
      journal      = {Brain Connectivity},
      volume       = {1},
      issn         = {2158-0014},
      address      = {New Rochelle, NY},
      publisher    = {Liebert},
      reportid     = {PreJuSER-17374},
      pages        = {219 - 231},
      year         = {2011},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Overt picture naming causes activation in both left and
                      right hemispheres as demonstrated by functional magnetic
                      resonance imaging (fMRI) studies. Unexpectedly, a previous
                      experiment revealed that there was no difference in brain
                      lateralization related to handedness. To understand the
                      mechanisms behind this phenomenon and to investigate the
                      influence that each hemisphere exerts over the other in more
                      detail, we analyzed the effective connectivity in the naming
                      network. More specifically, we examined the impact of
                      handedness on hemispheric interactions. Four brain regions
                      activated for correct naming in the previous fMRI experiment
                      served as volumes of interest: Bilateral fusiform gyrus (FG)
                      related to visual-semantic processing and bilateral
                      Brodmann's area (BA) 44 related to phonological processing.
                      We defined three dynamic causal models (DCMs) representing
                      different symmetrical connectivity patterns, compared them
                      using Bayesian model selection, and considered differential
                      connection strengths. For the majority of 31 participants,
                      the same model featuring early integration of
                      visual-semantic processing and independent phonological
                      processing was optimal. This also held true if
                      right-handers, left-handers, and ambidexters were considered
                      as independent groups. For left-handers, the connection of
                      right FG and right BA 44 was significantly stronger compared
                      with the other two groups, and it was significantly stronger
                      than its left-hemisphere equivalent. In right-handers, the
                      according left-hemisphere connection was significant, but
                      connectivities were rather symmetrical. These findings
                      reveal significant and unique right-hemisphere contributions
                      to word production.},
      cin          = {INM-1 / INM-2},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-2-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22433050},
      doi          = {10.1089/brain.2011.0024},
      url          = {https://juser.fz-juelich.de/record/17374},
}