001     17390
005     20210129210655.0
024 7 _ |2 DOI
|a 10.1016/j.ijms.2011.03.0110
024 7 _ |2 WOS
|a WOS:000295864100032
037 _ _ |a PreJuSER-17390
041 _ _ |a eng
082 _ _ |a 530
084 _ _ |2 WoS
|a Physics, Atomic, Molecular & Chemical
084 _ _ |2 WoS
|a Spectroscopy
100 1 _ |a Osterholt, T.
|b 0
|u FZJ
|0 P:(DE-Juel1)VDB95269
245 _ _ |a IMAGENA: Image Generation and Analysis - An Interactive Software Tool handling LA-ICP MS Data
260 _ _ |a [S.l.]
|b Elsevier Science
|c 2011
300 _ _ |a
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a International Journal of Mass Spectrometry
|x 1387-3806
|0 2787
|y 1
|v 307
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a Metals are involved in many processes of life. They are needed for enzymatic reactions, are involved in healthy processes but also yield diseases if the metal homeostasis is disordered. Therefore, the interest to assess the spatial distribution of metals is rising in biomedical science. Imaging metal (and non-metal) isotopes by laser ablation mass spectrometry with inductively coupled plasma (LA-ICP-MS) requires a special software solution to process raw data obtained by scanning a sample line-by-line. As no software ready to use was available we developed an interactive software tool for Image Generation and Analysis (IMAGENA). Unless optimised for LA-ICP-MS, IMAGENA can handle other raw data as well. The general purpose was to reconstruct images from a continuous list of raw data points, to visualise these images, and to convert them into a commonly readable image file format that can be further analysed by standard image analysis software. The generation of the image starts with loading a text file that holds a data column of every measured isotope. Specifying general spatial domain settings like the data offset and the image dimensions is done by the user getting a direct feedback by means of a preview image. IMAGENA provides tools for calibration and to correct for a signal drift in the y-direction. Images are visualised in greyscale as well a pseudo-colours with possibilities for contrast enhancement. Image analysis is performed in terms of smoothed line plots in row and column direction. (C) 2011 Elsevier B.V. All rights reserved.
536 _ _ |0 G:(DE-Juel1)FUEK409
|2 G:(DE-HGF)
|x 0
|c FUEK409
|a Funktion und Dysfunktion des Nervensystems (FUEK409)
536 _ _ |a 89574 - Theory, modelling and simulation (POF2-89574)
|0 G:(DE-HGF)POF2-89574
|c POF2-89574
|x 1
|f POF II T
588 _ _ |a Dataset connected to Web of Science
650 _ 7 |a J
|2 WoSType
653 2 0 |2 Author
|a LA-ICP-MS
653 2 0 |2 Author
|a Image generation
653 2 0 |2 Author
|a Image analysis
653 2 0 |2 Author
|a Graphical user interface
700 1 _ |a Salber, D.
|b 1
|0 P:(DE-HGF)0
700 1 _ |a Matusch, A.
|b 2
|u FZJ
|0 P:(DE-Juel1)138474
700 1 _ |a Becker, J.S.
|b 3
|u FZJ
|0 P:(DE-Juel1)VDB96675
700 1 _ |a Palm, C.
|b 4
|0 P:(DE-HGF)0
773 _ _ |a 10.1016/j.ijms.2011.03.0110
|g Vol. 307
|q 307
|0 PERI:(DE-600)1484635-4
|t International journal of mass spectrometry
|v 307
|y 2011
|x 1387-3806
856 7 _ |u http://dx.doi.org/10.1016/j.ijms.2011.03.0110
909 C O |o oai:juser.fz-juelich.de:17390
|p VDB
913 2 _ |a DE-HGF
|b Key Technologies
|l Decoding the Human Brain
|1 G:(DE-HGF)POF3-570
|0 G:(DE-HGF)POF3-574
|2 G:(DE-HGF)POF3-500
|v Theory, modelling and simulation
|x 0
913 1 _ |a DE-HGF
|0 G:(DE-HGF)POF2-89574
|v Theory, modelling and simulation
|x 1
|4 G:(DE-HGF)POF
|1 G:(DE-HGF)POF3-890
|3 G:(DE-HGF)POF3
|2 G:(DE-HGF)POF3-800
|b Programmungebundene Forschung
|l ohne Programm
914 1 _ |y 2011
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k INM-1
|l Strukturelle und funktionelle Organisation des Gehirns
|g INM
|0 I:(DE-Juel1)INM-1-20090406
|x 0
920 1 _ |k INM-2
|l Molekulare Organisation des Gehirns
|g INM
|0 I:(DE-Juel1)INM-2-20090406
|x 1
920 1 _ |k INM-4
|l Physik der Medizinischen Bildgebung
|g INM
|0 I:(DE-Juel1)INM-4-20090406
|x 2
970 _ _ |a VDB:(DE-Juel1)131845
980 _ _ |a VDB
980 _ _ |a ConvertedRecord
980 _ _ |a journal
980 _ _ |a I:(DE-Juel1)INM-1-20090406
980 _ _ |a I:(DE-Juel1)INM-2-20090406
980 _ _ |a I:(DE-Juel1)INM-4-20090406
980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)INM-2-20090406
981 _ _ |a I:(DE-Juel1)INM-4-20090406


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21