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@ARTICLE{Herold:17573,
      author       = {Herold, C. and Palomero-Gallagher, N. and Güntürkün, O.
                      and Zilles, K.},
      title        = {{S}erotonin 5-{HT}1{A} {R}eceptor {B}inding {S}ites in the
                      {B}rain of the {P}igeon ({C}olumba livia)},
      journal      = {Neuroscience},
      volume       = {200},
      issn         = {0306-4522},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {PreJuSER-17573},
      pages        = {1 - 12},
      year         = {2012},
      note         = {Supported by a grant from the BMBF through the Bernstein
                      Focus Group "Varying Tunes" to OG.},
      abstract     = {Present knowledge about the serotonergic system in
                      birdbrains is very limited, although the pigeon was used as
                      an animal model in various studies focused on the behavioral
                      effects of serotonergic transmission. In the mammalian brain
                      the 5-HT(1A) receptor is the most widespread serotonin
                      receptor type, and is involved in various functions. Less is
                      known about the distribution of 5-HT(1A) receptors in the
                      avian species. Therefore, we analyzed serotonin 5-HT(1A)
                      receptor binding sites in the pigeon brain using
                      quantitative in vitro receptor autoradiography with the
                      selective radioligand
                      [³H]-8-hydroxy-2-(di-n-propylamino)tetralin
                      ([³H]-8-OH-DPAT). The receptor is differentially
                      distributed throughout the pigeon brain. High levels of
                      5-HT(1A) receptors are found in the nucleus pretectalis
                      (PT). Moderate densities were detected in the tectum, as
                      well as in the telencephalic nidopallium and hyperpallium.
                      Very low levels were found in the hippocampal formation, the
                      amygdaloid complex, the basal ganglia, and several thalamic
                      nuclei. Furthermore, local variations in 5-HT(1A) receptor
                      densities support the concept of further subdivisions of the
                      entopallium. The regional distribution patterns of 5-HT(1A)
                      receptors mostly display a similar distribution as found in
                      homologue brain structures of mammals.},
      keywords     = {8-Hydroxy-2-(di-n-propylamino)tetralin: pharmacokinetics /
                      Analysis of Variance / Animals / Autoradiography / Binding
                      Sites: drug effects / Binding Sites: physiology / Brain:
                      drug effects / Brain: metabolism / Brain Mapping /
                      Columbidae / Receptors, Serotonin, 5-HT1: metabolism /
                      Serotonin Receptor Agonists: pharmacokinetics / Tritium:
                      pharmacokinetics / Receptors, Serotonin, 5-HT1 (NLM
                      Chemicals) / Serotonin Receptor Agonists (NLM Chemicals) /
                      Tritium (NLM Chemicals) /
                      8-Hydroxy-2-(di-n-propylamino)tetralin (NLM Chemicals) / J
                      (WoSType)},
      cin          = {INM-2},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
                      89571 - Connectivity and Activity (POF2-89571)},
      pid          = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
      shelfmark    = {Neurosciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22100786},
      UT           = {WOS:000299302300001},
      doi          = {10.1016/j.neuroscience.2011.10.050},
      url          = {https://juser.fz-juelich.de/record/17573},
}