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@ARTICLE{Rabe:183568,
author = {Rabe, Christian and Fleige, Emanuel and Vogtt, Karsten and
Szekely, Noemi and Lindner, Peter and Burchard, Walther and
Haag, Rainer and Ballauff, Matthias},
title = {{T}he multi-domain nanoparticle structure of a universal
core-multi-shell nanocarrier},
journal = {Polymer},
volume = {55},
number = {26},
issn = {0032-3861},
address = {Oxford},
publisher = {Elsevier Science},
reportid = {FZJ-2014-06862},
pages = {6735 - 6742},
year = {2014},
abstract = {Nanoparticles with a multi-domain structure have been
identified as a new class of highly potent nanocarriers with
a dual transport mechanism for polar and non-polar guests.
In this paper we present a detailed analysis of their
spatial structure, which has been analyzed by small-angle
neutron scattering (SANS) including contrast variation. The
nanocarriers consist of a hyperbranched polyglycerol (hPG)
core onto which di-block segments consisting of non-polar
alkyl chains and hydrophilic poly(ethylene glycol) methyl
ether (mPEG) has been grafted. The hPG cores have been
analyzed separately for comparison. SANS demonstrates that
the hPG-cores can be described as fractal structures. The
nanocarriers form rather compact structures in the non-polar
solvent toluene. A fractal structure with a correspondingly
rough surface is found here as well, which is explained by
the backfolding of the hydrophilic mPEG-chains in the
non-polar environment. In water the nanocarriers associate
to form well-defined nanoparticle clusters with an
ellipsoidal shape. Contrast variation demonstrates that
these particles have no distinct core–shell structure but
the separation of the incompatible parts of the structure
takes place on a much smaller length scale.},
cin = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
(München) ; JCNS-FRM-II / Neutronenstreuung ; JCNS-1 /
ICS-1},
ddc = {540},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106 / I:(DE-Juel1)ICS-1-20110106},
pnm = {54G - JCNS (POF2-54G24)},
pid = {G:(DE-HGF)POF2-54G24},
experiment = {EXP:(DE-MLZ)KWS1-20140101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000346887700012},
doi = {10.1016/j.polymer.2014.10.061},
url = {https://juser.fz-juelich.de/record/183568},
}