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@ARTICLE{DellaVecchia:183573,
author = {Della Vecchia, Nicola Fyodor and Luchini, Alessandra and
Napolitano, Alessandra and D’Errico, Gerardino and
Vitiello, Giuseppe and Szekely, Noemi and d’Ischia, Marco
and Paduano, Luigi},
title = {{T}ris {B}uffer {M}odulates {P}olydopamine {G}rowth,
{A}ggregation, and {P}aramagnetic {P}roperties},
journal = {Langmuir},
volume = {30},
number = {32},
issn = {1520-5827},
address = {Washington, DC},
publisher = {ACS Publ.},
reportid = {FZJ-2014-06867},
pages = {9811 - 9818},
year = {2014},
abstract = {Despite the growing technological interest of polydopamine
(dopamine melanin)-based coatings for a broad variety of
applications, the factors governing particle size, shape,
and electronic properties of this bioinspired
multifunctional material have remained little understood.
Herein, we report a detailed characterization of
polydopamine growth, particle morphology, and paramagnetic
properties as a function of dopamine concentration and
nature of the buffer (pH 8.5). Dynamic Light Scattering data
revealed an increase in the hydrodynamic radii (Rh) of
melanin particles with increasing dopamine concentration in
all buffers examined, especially in phosphate buffer.
Conversely, a marked inhibition of particle growth was
apparent in Tris buffer, with Rh remaining as low as <100 nm
during polymerization of 0.5 mM dopamine. Small angle
neutron scattering data suggested formation of bidimensional
structures in phosphate or bicarbonate buffers, while
apparently three-dimensional fractal objects prevailed in
Tris buffer. Finally, electron paramagnetic resonance
spectra revealed a broader signal amplitude with a peculiar
power saturation decay profile for polydopamine samples
prepared in Tris buffer, denoting more homogeneous
paramagnetic centers with respect to similar samples
obtained in phosphate and bicarbonate buffers. Overall,
these results disclose Tris buffer as an efficient modulator
of polydopamine buildup and properties for the rational
control and fine-tuning of melanin aggregate size,
morphology, and free radical behavior.},
cin = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
(München) ; JCNS-FRM-II / Neutronenstreuung ; JCNS-1 /
ICS-1},
ddc = {670},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106 / I:(DE-Juel1)ICS-1-20110106},
pnm = {54G - JCNS (POF2-54G24)},
pid = {G:(DE-HGF)POF2-54G24},
experiment = {EXP:(DE-MLZ)KWS2-20140101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000340701300022},
doi = {10.1021/la501560z},
url = {https://juser.fz-juelich.de/record/183573},
}