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@ARTICLE{Eickhoff:1852,
author = {Eickhoff, S. B. and Dafotakis, M. and Grefkes, M. and
Stöcker, T. and Shah, J. N. and Schnitzler, A. and Zilles,
K. and Siebler, M.},
title = {f{MRI} reveals cognitive and emotional processing in a
long-term comatose patient},
journal = {Experimental neurology},
volume = {214},
issn = {0014-4886},
address = {Amsterdam [u.a.]},
publisher = {Elsevier},
reportid = {PreJuSER-1852},
pages = {240 - 246},
year = {2008},
note = {This Human Brain Project/Neuroinformatics research was
funded by the NIBIB, NINDS and NIMH. K.Z. acknowledges
funding by the Deutsche Forschungsgemeinschaft (KFO-112) and
the Volkswagenstiftung.},
abstract = {We report on a 41-year old woman with prolonged comatose
unresponsiveness following traumatic head injury. Structural
MRI showed bilateral midbrain damage and ventriculomegalia.
Functional MRI revealed robust cortical responses to visual,
auditory and tactile stimulation. Speech stimuli moreover
consistently elicited activation in Broca's and Wernicke's
areas. Familiar speakers and direct addressing evoked
significantly stronger amygdala activation than unfamiliar
speakers and neutral phrases. This study hence demonstrates
the potential of functional neuroimaging in the
investigation of residual higher cortical functions in
unresponsive comatose patients.},
keywords = {Acoustic Stimulation / Adult / Amygdala: physiology /
Cognition: physiology / Coma: physiopathology / Emotions:
physiology / Female / Frontal Lobe: physiology / Humans /
Magnetic Resonance Imaging / Persistent Vegetative State:
physiopathology / Photic Stimulation / Physical Stimulation
/ Speech Perception: physiology / Temporal Lobe: physiology
/ J (WoSType)},
cin = {INB-3 / JARA-BRAIN},
ddc = {610},
cid = {I:(DE-Juel1)INB-3-20090406 / $I:(DE-82)080010_20140620$},
pnm = {Funktion und Dysfunktion des Nervensystems},
pid = {G:(DE-Juel1)FUEK409},
shelfmark = {Neurosciences},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:18789930},
UT = {WOS:000261483900010},
doi = {10.1016/j.expneurol.2008.08.007},
url = {https://juser.fz-juelich.de/record/1852},
}