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@ARTICLE{Warbrick:186048,
author = {Warbrick, Tracy and Reske, Martina and Shah, N. J.},
title = {{T}ransferring {C}ognitive {T}asks {B}etween {B}rain
{I}maging {M}odalities: {I}mplications for {T}ask {D}esign
and {R}esults {I}nterpretation in f{MRI} {S}tudies},
journal = {Journal of visualized experiments},
volume = {91},
issn = {1940-087X},
address = {[S.l.]},
publisher = {JoVE},
reportid = {FZJ-2015-00149},
pages = {51793},
year = {2014},
abstract = {As cognitive neuroscience methods develop, established
experimental tasks are used with emerging brain imaging
modalities. Here transferring a paradigm (the visual oddball
task) with a long history of behavioral and
electroencephalography (EEG) experiments to a functional
magnetic resonance imaging (fMRI) experiment is considered.
The aims of this paper are to briefly describe fMRI and when
its use is appropriate in cognitive neuroscience; illustrate
how task design can influence the results of an fMRI
experiment, particularly when that task is borrowed from
another imaging modality; explain the practical aspects of
performing an fMRI experiment. It is demonstrated that
manipulating the task demands in the visual oddball task
results in different patterns of blood oxygen level
dependent (BOLD) activation. The nature of the fMRI BOLD
measure means that many brain regions are found to be active
in a particular task. Determining the functions of these
areas of activation is very much dependent on task design
and analysis. The complex nature of many fMRI tasks means
that the details of the task and its requirements need
careful consideration when interpreting data. The data show
that this is particularly important in those tasks relying
on a motor response as well as cognitive elements and that
covert and overt responses should be considered where
possible. Furthermore, the data show that transferring an
EEG paradigm to an fMRI experiment needs careful
consideration and it cannot be assumed that the same
paradigm will work equally well across imaging modalities.
It is therefore recommended that the design of an fMRI study
is pilot tested behaviorally to establish the effects of
interest and then pilot tested in the fMRI environment to
ensure appropriate design, implementation and analysis for
the effects of interest.},
cin = {INM-6 / IAS-6 / INM-4},
ddc = {570},
cid = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)IAS-6-20130828 /
I:(DE-Juel1)INM-4-20090406},
pnm = {331 - Signalling Pathways and Mechanisms in the Nervous
System (POF2-331) / 89573 - Neuroimaging (POF2-89573)},
pid = {G:(DE-HGF)POF2-331 / G:(DE-HGF)POF2-89573},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000349301100036},
pubmed = {pmid:25285453},
doi = {10.3791/51793},
url = {https://juser.fz-juelich.de/record/186048},
}