% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Pool:187309,
      author       = {Pool, Eva-Maria and Rehme, Anne K. and Eickhoff, Simon and
                      Fink, Gereon R. and Grefkes, Christian},
      title        = {{F}unctional resting-state connectivity of the human motor
                      network: {D}ifferences between right- and left-handers},
      journal      = {NeuroImage},
      volume       = {109},
      issn         = {1053-8119},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2015-00980},
      pages        = {298–306},
      year         = {2015},
      abstract     = {Handedness is associated with differences in activation
                      levels in various motor tasks performed with the dominant or
                      non-dominant hand. Here we tested whether handedness is
                      reflected in the functional architecture of the motor system
                      even in the absence of an overt motor task. Using
                      resting-state functional magnetic resonance imaging we
                      investigated 18 right- and 18 left-handers. Whole-brain
                      functional connectivity maps of the primary motor cortex
                      (M1), supplementary motor area (SMA), dorsolateral premotor
                      cortex (PMd), pre-SMA, inferior frontal junction and motor
                      putamen were compared between right- and left-handers. We
                      further used a multivariate linear support vector machine
                      (SVM) classifier to reveal the specificity of brain regions
                      for classifying handedness based on individual resting-state
                      maps. Using left M1 as seed region, functional connectivity
                      analysis revealed stronger interhemispheric functional
                      connectivity between left M1 and right PMd in right-handers
                      as compared to left-handers. This connectivity cluster
                      contributed to the individual classification of right- and
                      left-handers with $86.2\%$ accuracy. Consistently, also
                      seeding from right PMd yielded a similar
                      handedness-dependent effect in left M1, albeit with lower
                      classification accuracy $(78.1\%).$ Control analyses of the
                      other resting-state networks including the speech and the
                      visual network revealed no significant differences in
                      functional connectivity related to handedness. In
                      conclusion, our data revealed an intrinsically higher
                      functional connectivity in right-handers. These results may
                      help to explain that hand preference is more lateralized in
                      right-handers than in left-handers. Furthermore, enhanced
                      functional connectivity between left M1 and right PMd may
                      serve as an individual marker of handedness.},
      cin          = {INM-1 / INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-3-20090406},
      pnm          = {571 - Connectivity and Activity (POF3-571) / HBP - The
                      Human Brain Project (604102)},
      pid          = {G:(DE-HGF)POF3-571 / G:(EU-Grant)604102},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000349971600027},
      pubmed       = {pmid:25613438},
      doi          = {10.1016/j.neuroimage.2015.01.034},
      url          = {https://juser.fz-juelich.de/record/187309},
}