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@ARTICLE{Rahe:188894,
author = {Rahe, J. and Liesk, J. and Rosen, J. and Petrelli, A. and
Kaesberg, S. and Özgür, O. and Kessler, J. and Fink, G. R.
and Kalbe, E.},
title = {{S}ex {D}ifferences in {C}ognitive {T}raining {E}ffects of
{P}atients with {A}mnestic {M}ild {C}ognitive {I}mpairment.},
journal = {Aging, neuropsychology, and cognition},
volume = {22},
number = {5},
issn = {1382-5585},
address = {Lisse},
publisher = {Swets $\&$ Zeitlinger},
reportid = {FZJ-2015-02192},
pages = {620-638},
year = {2015},
abstract = {Cognitive training has been shown to be effective in
improving cognitive functions in patients with Mild
Cognitive Impairment (MCI). However, data on factors that
may influence training gains including sociodemographic
variables such as sex or age is rare. In this study, the
impact of sex on cognitive training effects was examined in
N = 32 age- and education-matched female (n = 16) and male
(n = 16) amnestic MCI patients (total sample: age M = 74.97,
SD = 5.21; education M = 13.50, SD = 3.11). Patients
participated in a six-week multidomain cognitive training
program including 12 sessions each 90 min twice weekly in
mixed groups with both women and men. Various cognitive
domains were assessed before and after the intervention.
Despite comparable baseline performance in women and men, we
found significant interaction effects Time × Sex in
immediate (p = .04) and delayed verbal episodic memory (p=
.045) as well as in working memory (p = .042) favoring the
female MCI patients. In contrast, the overall analyses with
the total sample did not reveal any significant
within-subject effects Time. In conclusion, our results give
preliminary evidence for stronger cognitive training
improvements of female compared to male MCI patients. More
generally, they emphasize the importance of sex-sensitive
evaluations of cognitive training effects. Possible
underlying mechanisms of the found sex differences are
discussed and directions for future research are given.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000356295400007},
pubmed = {pmid:25818876},
doi = {10.1080/13825585.2015.1028883},
url = {https://juser.fz-juelich.de/record/188894},
}