000190177 001__ 190177 000190177 005__ 20210129215530.0 000190177 0247_ $$2doi$$a10.1186/s40064-015-0869-y 000190177 0247_ $$2Handle$$a2128/9030 000190177 0247_ $$2WOS$$aWOS:000359200700001 000190177 0247_ $$2altmetric$$aaltmetric:21825899 000190177 0247_ $$2pmid$$apmid:25984436 000190177 037__ $$aFZJ-2015-03105 000190177 041__ $$aEnglish 000190177 082__ $$a600 000190177 1001_ $$0P:(DE-HGF)0$$aHaupt, W. F.$$b0$$eCorresponding author 000190177 245__ $$aComa and Cerebral Imaging. 000190177 260__ $$aLondon$$bBiomed Central$$c2015 000190177 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1439200636_17760 000190177 3367_ $$2DataCite$$aOutput Types/Journal article 000190177 3367_ $$00$$2EndNote$$aJournal Article 000190177 3367_ $$2BibTeX$$aARTICLE 000190177 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000190177 3367_ $$2DRIVER$$aarticle 000190177 520__ $$aThe clinical sign of coma is a common feature in critical care medicine. However, little information has been put forth on the correlations between coma and cerebral imaging methods. The purpose of the article is to compile the available information derived from various imaging methods and placing it in a context of clinical knowledge of coma and related states. The definition of coma and the cerebral structures responsible for consciousness are described; the mechanisms of cerebral lesions leading to impaired consciousness and coma are explained. Cerebral imaging methods provide a large array of information on the structural changes of brain tissue in the various diseases leading to coma. Circumscript lesions produce space-occupying masses that displace the brain, ultimately leading to various types of herniation. Generalized disease of the brain usually leads to diffuse brain swelling which also can cause herniation. Epileptic states, however, rarely are detectable by imaging methods and mandate EEG examinations. Another important aspect of imaging in coma is the increasing use of functional imaging methods, which can detect the function of loss of function in various areas of the brain and render information on the extent and severity of brain damage as well as on the prognosis of disease. The MRI methods of 1H-spectroscopy and diffusion tensor imaging may provide more functional information in the future. 000190177 536__ $$0G:(DE-HGF)POF3-572$$a572 - (Dys-)function and Plasticity (POF3-572)$$cPOF3-572$$fPOF III$$x0 000190177 7001_ $$0P:(DE-HGF)0$$aHansen, H. C.$$b1 000190177 7001_ $$0P:(DE-HGF)0$$aJanzen, R. W. C.$$b2 000190177 7001_ $$0P:(DE-HGF)0$$aFirsching, R.$$b3 000190177 7001_ $$0P:(DE-Juel1)143792$$aGalldiks, N.$$b4 000190177 773__ $$0PERI:(DE-600)2661116-8$$a10.1186/s40064-015-0869-y$$pArticle 180$$tSpringerPlus$$v4$$x2193-1801$$y2015 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.pdf$$yOpenAccess 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.gif?subformat=icon$$xicon$$yOpenAccess 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.jpg?subformat=icon-180$$xicon-180$$yOpenAccess 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.jpg?subformat=icon-640$$xicon-640$$yOpenAccess 000190177 8564_ $$uhttps://juser.fz-juelich.de/record/190177/files/s40064-015-0869-y.pdf?subformat=pdfa$$xpdfa$$yOpenAccess 000190177 909CO $$ooai:juser.fz-juelich.de:190177$$pdnbdelivery$$pVDB$$pdriver$$popen_access$$popenaire 000190177 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000190177 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000190177 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ 000190177 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess 000190177 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR 000190177 9141_ $$y2015 000190177 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)143792$$aForschungszentrum Jülich GmbH$$b4$$kFZJ 000190177 9130_ $$0G:(DE-HGF)POF2-333$$1G:(DE-HGF)POF2-330$$2G:(DE-HGF)POF2-300$$aDE-HGF$$bGesundheit$$lFunktion und Dysfunktion des Nervensystems$$vPathophysiological Mechanisms of Neurological and Psychiatric Diseases$$x0 000190177 9131_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0 000190177 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0 000190177 980__ $$ajournal 000190177 980__ $$aVDB 000190177 980__ $$aUNRESTRICTED 000190177 980__ $$aI:(DE-Juel1)INM-3-20090406 000190177 980__ $$aFullTexts 000190177 9801_ $$aFullTexts