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@ARTICLE{Reid:200952,
author = {Reid, Andrew and Bzdok, Danilo and Langner, Robert and Fox,
Peter T and Laird, Angela R and Amunts, Katrin and Eickhoff,
Simon and Eickhoff, Claudia R},
title = {{M}ultimodal connectivity mapping of the human left
anterior and posterior lateral prefrontal cortex.},
journal = {Brain structure $\&$ function},
volume = {221},
number = {5},
issn = {1863-2661},
address = {Berlin},
publisher = {Springer},
reportid = {FZJ-2015-03290},
pages = {2589-2605},
year = {2016},
abstract = {Working memory is essential for many of our distinctly
human abilities, including reasoning, problem solving, and
planning. Research spanning many decades has helped to
refine our understanding of this high-level function as
comprising several hierarchically organized components, some
which maintain information in the conscious mind, and others
which manipulate and reorganize this information in useful
ways. In the neocortex, these processes are likely
implemented by a distributed frontoparietal network, with
more posterior regions serving to maintain volatile
information, and more anterior regions subserving the
manipulation of this information. Recent meta-analytic
findings have identified the anterior lateral prefrontal
cortex, in particular, as being generally engaged by working
memory tasks, while the posterior lateral prefrontal cortex
was more strongly associated with the cognitive load
required by these tasks. These findings suggest specific
roles for these regions in the cognitive control processes
underlying working memory. To further characterize these
regions, we applied three distinct seed-based methods for
determining cortical connectivity. Specifically, we employed
meta-analytic connectivity mapping across task-based fMRI
experiments, resting-state BOLD correlations, and VBM-based
structural covariance. We found a frontoparietal pattern of
convergence which strongly resembled the working memory
networks identified in previous research. A contrast between
anterior and posterior parts of the lateral prefrontal
cortex revealed distinct connectivity patterns consistent
with the idea of a hierarchical organization of
frontoparietal networks. Moreover, we found a distributed
network that was anticorrelated with the anterior seed
region, which included most of the default mode network and
a subcomponent related to social and emotional processing.
These findings fit well with the internal attention model of
working memory, in which representation of information is
processed according to an anteroposterior gradient of
abstract-to-concrete representations.},
cin = {INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {571 - Connectivity and Activity (POF3-571) / HBP - The
Human Brain Project (604102) / SMHB - Supercomputing and
Modelling for the Human Brain (HGF-SMHB-2013-2017)},
pid = {G:(DE-HGF)POF3-571 / G:(EU-Grant)604102 /
G:(DE-Juel1)HGF-SMHB-2013-2017},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:25982222},
UT = {WOS:000377012100013},
doi = {10.1007/s00429-015-1060-5},
url = {https://juser.fz-juelich.de/record/200952},
}