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@ARTICLE{MuhleKarbe:200954,
author = {Muhle-Karbe, Paul S and Derrfuss, Jan and Lynn, Margaret T
and Neubert, Franz X and Fox, Peter T and Brass, Marcel and
Eickhoff, Simon},
title = {{C}o-{A}ctivation-{B}ased {P}arcellation of the {L}ateral
{P}refrontal {C}ortex {D}elineates the {I}nferior {F}rontal
{J}unction {A}rea.},
journal = {Cerebral cortex},
volume = {26},
number = {5},
issn = {1460-2199},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2015-03292},
pages = {2225-2241},
year = {2016},
abstract = {The inferior frontal junction (IFJ) area, a small region in
the posterior lateral prefrontal cortex (LPFC), has received
increasing interest in recent years due to its central
involvement in the control of action, attention, and memory.
Yet, both its function and anatomy remain controversial.
Here, we employed a meta-analytic parcellation of the left
LPFC to show that the IFJ can be isolated based on its
specific functional connections. A seed region, oriented
along the left inferior frontal sulcus (IFS), was subdivided
via cluster analyses of voxel-wise whole-brain co-activation
patterns. The ensuing clusters were characterized by their
unique connections, the functional profiles of associated
experiments, and an independent topic mapping approach. A
cluster at the posterior end of the IFS matched previous
descriptions of the IFJ in location and extent and could be
distinguished from a more caudal cluster involved in motor
control, a more ventral cluster involved in linguistic
processing, and 3 more rostral clusters involved in other
aspects of cognitive control. Overall, our findings
highlight that the IFJ constitutes a core functional unit
within the frontal lobe and delineate its borders.
Implications for the IFJ's role in human cognition and the
organizational principles of the frontal lobe are
discussed.},
cin = {INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {571 - Connectivity and Activity (POF3-571) / HBP - The
Human Brain Project (604102)},
pid = {G:(DE-HGF)POF3-571 / G:(EU-Grant)604102},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:25899707},
UT = {WOS:000377469500032},
doi = {10.1093/cercor/bhv073},
url = {https://juser.fz-juelich.de/record/200954},
}