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@INBOOK{Feldmeyer:201253,
      author       = {Feldmeyer, Dirk and Lübke, Joachim},
      title        = {{T}he {A}xon of {E}xcitatory {N}eurons in the {N}eocortex:
                      {P}rojection {P}atterns and {T}arget {S}pecificity},
      address      = {Berlin},
      publisher    = {Springer-Verlag},
      reportid     = {FZJ-2015-03558},
      isbn         = {978-1-4419-1675-4},
      pages        = {157-178},
      year         = {2010},
      comment      = {New Aspects of Axonal Structure and Function},
      booktitle     = {New Aspects of Axonal Structure and
                       Function},
      abstract     = {The neocortex of higher mammals consists of six layers and
                      three major populations of neurons, the majority of which
                      are excitatory pyramidal cells in layers 2/3, 5 and 6,
                      so-called spiny stellate and star pyramidal neurons in layer
                      4 and a very heterogeneous population of GABAergic
                      interneurons found throughout all cortical layers. These
                      neurons form individual, highly specific microcircuits with
                      each other thereby forming networks like the cortical
                      column. This chapter will summarize and discuss the axonal
                      arborization of principal excitatory neurons and it’s
                      implication for neocortical connectivity. It was long
                      thought that pyramidal cells represent a rather stereotyped
                      class of neurons both with respect to their dendritic
                      configuration and their axonal arborization. There is,
                      however, growing evidence that pyramidal cells show profound
                      structural and functional differences, not only between
                      cortical layers but also within a given layer. Principal
                      neurons except spiny stellate neurons and star pyramidal
                      cells in layer 4 generally have two axonal domains: a
                      vertically oriented domain that projects throughout the
                      cortical column into the white matter and from there either
                      to the contralateral hemisphere or to various subcortical
                      brain regions. The second domain forms a discontinuous
                      system of long-range horizontal projections either within a
                      given cortical or between cortical areas within a given
                      sensory or even between different sensory systems. In
                      summary, principal excitatory neurons in the neocortex vary
                      substantially in their axonal projection patterns and the
                      cellular as well as subcellular input and target specificity
                      of their axons thereby contributing to the enormous
                      computational capacity of the neocortex.},
      cin          = {INM-2},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {331 - Signalling Pathways and Mechanisms in the Nervous
                      System (POF2-331)},
      pid          = {G:(DE-HGF)POF2-331},
      typ          = {PUB:(DE-HGF)7},
      UT           = {WOS:000281822600009},
      doi          = {10.1007/978-1-4419-1676-1_9},
      url          = {https://juser.fz-juelich.de/record/201253},
}