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@ARTICLE{Costa:201255,
      author       = {Costa, Ana Sofia and Reich, Arno and Fimm, Bruno and
                      Ketteler, Simon Thomas and Schulz, Joerg Bernhard and Reetz,
                      Kathrin},
      title        = {{E}vidence of the {S}ensitivity of the {M}o{CA} {A}lternate
                      {F}orms in {M}onitoring {C}ognitive {C}hange in {E}arly
                      {A}lzheimer's {D}isease},
      journal      = {Dementia and geriatric cognitive disorders},
      volume       = {37},
      number       = {1-2},
      issn         = {1421-9824},
      address      = {Basel},
      publisher    = {Karger},
      reportid     = {FZJ-2015-03560},
      pages        = {95 - 103},
      year         = {2014},
      abstract     = {Background/Aims: There is an increasing interest in using
                      the Montreal Cognitive Assessment (MoCA) test as a
                      monitoring tool in Alzheimer's disease (AD) in both research
                      and clinical settings. Our aim was to investigate the
                      utility of alternate forms of the MoCA in detecting
                      cognitive deterioration in a sample of early AD patients
                      followed longitudinally in an outpatient memory clinic.
                      Method: Twenty-five patients with early-stage AD (prodromal
                      or mild dementia) were administered the original version and
                      one of two previously validated alternate forms of the MoCA
                      within an interval of about 1 year. The decline over time
                      and the rate of change of the MoCA were compared to the
                      total score of a standardized neuropsychological assessment
                      battery (Consortium to Establish a Registry of Alzheimer's
                      Disease; CERAD-Plus). Responsiveness to change was
                      determined by calculating standard response means and the
                      respective effect sizes. Results: Sixty percent of the
                      sample showed a clinical decline on the clinical dementia
                      rating (CDR) scale. There was significant deterioration in
                      the MoCA and CERAD total scores. Conclusion: The results
                      demonstrate that the MoCA is capable of detecting change
                      over time and seems to be a valid tool with small to
                      moderate sensitivity for monitoring cognitive change in
                      early AD.},
      cin          = {INM-4 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$},
      pnm          = {332 - Imaging the Living Brain (POF2-332)},
      pid          = {G:(DE-HGF)POF2-332},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000331808200009},
      doi          = {10.1159/000351864},
      url          = {https://juser.fz-juelich.de/record/201255},
}