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| Hauptseite > Publikationsdatenbank > Evidence of the Sensitivity of the MoCA Alternate Forms in Monitoring Cognitive Change in Early Alzheimer's Disease > print |
| Hauptseite > Publikationsdatenbank > Evidence of the Sensitivity of the MoCA Alternate Forms in Monitoring Cognitive Change in Early Alzheimer's Disease > print |
| 001 | 201255 | ||
| 005 | 20210129215708.0 | ||
| 024 | 7 | _ | |a 10.1159/000351864 |2 doi |
| 024 | 7 | _ | |a 1013-7424 |2 ISSN |
| 024 | 7 | _ | |a 1420-8008 |2 ISSN |
| 024 | 7 | _ | |a 1421-9824 |2 ISSN |
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| 037 | _ | _ | |a FZJ-2015-03560 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Costa, Ana Sofia |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Evidence of the Sensitivity of the MoCA Alternate Forms in Monitoring Cognitive Change in Early Alzheimer's Disease |
| 260 | _ | _ | |a Basel |c 2014 |b Karger |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1433832583_26782 |2 PUB:(DE-HGF) |
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| 336 | 7 | _ | |a article |2 DRIVER |
| 520 | _ | _ | |a Background/Aims: There is an increasing interest in using the Montreal Cognitive Assessment (MoCA) test as a monitoring tool in Alzheimer's disease (AD) in both research and clinical settings. Our aim was to investigate the utility of alternate forms of the MoCA in detecting cognitive deterioration in a sample of early AD patients followed longitudinally in an outpatient memory clinic. Method: Twenty-five patients with early-stage AD (prodromal or mild dementia) were administered the original version and one of two previously validated alternate forms of the MoCA within an interval of about 1 year. The decline over time and the rate of change of the MoCA were compared to the total score of a standardized neuropsychological assessment battery (Consortium to Establish a Registry of Alzheimer's Disease; CERAD-Plus). Responsiveness to change was determined by calculating standard response means and the respective effect sizes. Results: Sixty percent of the sample showed a clinical decline on the clinical dementia rating (CDR) scale. There was significant deterioration in the MoCA and CERAD total scores. Conclusion: The results demonstrate that the MoCA is capable of detecting change over time and seems to be a valid tool with small to moderate sensitivity for monitoring cognitive change in early AD. |
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| 700 | 1 | _ | |a Reich, Arno |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Fimm, Bruno |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Ketteler, Simon Thomas |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Schulz, Joerg Bernhard |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Reetz, Kathrin |0 P:(DE-Juel1)162203 |b 5 |e Corresponding Author |
| 773 | _ | _ | |a 10.1159/000351864 |g Vol. 37, no. 1-2, p. 95 - 103 |0 PERI:(DE-600)1482186-2 |n 1-2 |p 95 - 103 |t Dementia and geriatric cognitive disorders |v 37 |y 2014 |x 1421-9824 |
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