%0 Journal Article
%A Stadler, Andreas
%A Monkenbusch, Michael
%A Biehl, Ralf
%A Richter, Dieter
%A Ollivier, Jacques
%T Neutron Spin-Echo and TOF Reveals Protein Dynamics in Solution
%J Journal of the Physical Society of Japan
%V 82
%N Suppl.A
%@ 1347-4073
%C Tokyo
%I The Physical Society of Japan
%M FZJ-2015-03980
%P SA016 -
%D 2013
%X The ps to ns dynamics of the protein alcohol dehydrogenase (ADH) has been measured in dilute solution by time-of-flight (TOF) neutron spectroscopy. The investigation extends previous experiments on ADH solutions with neutron-spin-echo spectroscopy. The interpretation of TOF experiments used the diffusion data from NSE as input to decribe the observed slow component of the quasielastic spectra, in addition a fast component to be associated to mobile groups in the protein could be observed. The description within a simple model for translational and rotational diffusion and a fraction of protons with confined local mobility is given together with a novel method to accurately and efficiently account for the instrumental resolution.
%F PUB:(DE-HGF)16
%9 Journal Article
%U <Go to ISI:>//WOS:000341649900016
%R 10.7566/JPSJS.82SA.SA016
%U https://juser.fz-juelich.de/record/201686