TY  - JOUR
AU  - Stadler, Andreas
AU  - Monkenbusch, Michael
AU  - Biehl, Ralf
AU  - Richter, Dieter
AU  - Ollivier, Jacques
TI  - Neutron Spin-Echo and TOF Reveals Protein Dynamics in Solution
JO  - Journal of the Physical Society of Japan
VL  - 82
IS  - Suppl.A
SN  - 1347-4073
CY  - Tokyo
PB  - The Physical Society of Japan
M1  - FZJ-2015-03980
SP  - SA016 -
PY  - 2013
AB  - The ps to ns dynamics of the protein alcohol dehydrogenase (ADH) has been measured in dilute solution by time-of-flight (TOF) neutron spectroscopy. The investigation extends previous experiments on ADH solutions with neutron-spin-echo spectroscopy. The interpretation of TOF experiments used the diffusion data from NSE as input to decribe the observed slow component of the quasielastic spectra, in addition a fast component to be associated to mobile groups in the protein could be observed. The description within a simple model for translational and rotational diffusion and a fraction of protons with confined local mobility is given together with a novel method to accurately and efficiently account for the instrumental resolution.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000341649900016
DO  - DOI:10.7566/JPSJS.82SA.SA016
UR  - https://juser.fz-juelich.de/record/201686
ER  -