TY  - JOUR
AU  - von Polier, G. G.
AU  - Biskup, C. S.
AU  - Kötting, W. F.
AU  - Bubenzer, S.
AU  - Helmbold, K.
AU  - Eisert, A.
AU  - Gaber, T. J.
AU  - Zepf, F. D.
TI  - Change in electrodermal activity after acute tryptophan depletion associated with aggression in young people with attention deficit hyperactivity disorder (ADHD)
JO  - Journal of neural transmission
VL  - 121
IS  - 4
SN  - 1435-1463
CY  - Wien [u.a.]
PB  - Springer
M1  - FZJ-2015-04290
SP  - 451 - 455
PY  - 2014
AB  - We investigated the impact of acute tryptophan depletion (ATD) and reduced brain serotonin synthesis on physiological arousal in 15 young people with ADHD participating in an aggression-inducing game. ATD was not associated with altered physiological arousal, as indexed by electrodermal activity (EDA). Baseline aggression was negatively correlated with the mean ATD effect on EDA. In accordance with the low arousal theory related to aggressive behavior, subjects with reduced physiological responsiveness/lower electrodermal reactivity to ATD tended to display elevated externalizing behavior.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000333206100015
C6  - pmid:24292894
DO  - DOI:10.1007/s00702-013-1119-5
UR  - https://juser.fz-juelich.de/record/202001
ER  -