001     20233
005     20210129210743.0
024 7 _ |2 pmid
|a pmid:22387170
024 7 _ |2 pmc
|a pmc:PMC3321133
024 7 _ |2 DOI
|a 10.1016/j.neuroimage.2012.02.037
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|a WOS:000302926600046
037 _ _ |a PreJuSER-20233
041 _ _ |a eng
082 _ _ |a 610
084 _ _ |2 WoS
|a Neurosciences
084 _ _ |2 WoS
|a Neuroimaging
084 _ _ |2 WoS
|a Radiology, Nuclear Medicine & Medical Imaging
100 1 _ |0 P:(DE-Juel1)VDB75804
|a Jakobs, O.
|b 0
|u FZJ
245 _ _ |a Across-study and within-subject functional connectivity of a right-temporo-parietal junction subregion involved in stimulus-context integration
260 _ _ |a Orlando, Fla.
|b Academic Press
|c 2012
300 _ _ |a 2389 - 2398
336 7 _ |a Journal Article
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336 7 _ |a article
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440 _ 0 |0 4545
|a NeuroImage
|v 60
|x 1053-8119
|y 4
500 _ _ |a This work was partly funded by the Human Brain Project (R01-MH074457; A.R.L., S.B.E., P.T.F), the Initiative and Networking Fund of the Helmholtz Association within the Helmholtz Alliance on Systems Biology (Human Brain Model; K.Z., S.B.E.) and the DFG (IRTG 1328, S.B.E.).
520 _ _ |a Bidirectional integration between sensory stimuli and contextual framing is fundamental to action control. Stimuli may entail context-dependent actions, while temporal or spatial characteristics of a stimulus train may establish a contextual framework for upcoming stimuli. Here we aimed at identifying core areas for stimulus-context integration and delineated their functional connectivity (FC) using meta-analytic connectivity modeling (MACM) and analysis of resting-state networks. In a multi-study conjunction, consistently increased activity under higher demands on stimulus-context integration was predominantly found in the right temporo-parietal junction (TPJ), which represented the largest cluster of overlap and was thus used as the seed for the FC analyses. The conjunction between task-dependent (MACM) and task-free (resting state) FC of the right TPJ revealed a shared network comprising bilaterally inferior parietal and frontal cortices, anterior insula, premotor cortex, putamen and cerebellum, i.e., a 'ventral' action/attention network. Stronger task-dependent (vs. task-free) connectivity was observed with the pre-SMA, dorsal premotor cortex, intraparietal sulcus, basal ganglia and primary sensori motor cortex, while stronger resting-state (vs. task-dependent) connectivity was found with the dorsolateral prefrontal and medial parietal cortex. Our data provide strong evidence that the right TPJ may represent a key region for the integration of sensory stimuli and contextual frames in action control. Task-dependent associations with regions related to stimulus processing and motor responses indicate that the right TPJ may integrate 'collaterals' of sensory processing and apply (ensuing) contextual frames, most likely via modulation of preparatory loops. Given the pattern of resting-state connectivity, internal states and goal representations may provide the substrates for the contextual integration within the TPJ in the absence of a specific task.
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588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Attention: physiology
650 _ 2 |2 MeSH
|a Brain: physiology
650 _ 2 |2 MeSH
|a Brain Mapping
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Magnetic Resonance Imaging
650 _ 2 |2 MeSH
|a Neural Pathways: physiology
650 _ 2 |2 MeSH
|a Psychomotor Performance: physiology
650 _ 2 |2 MeSH
|a Rest: physiology
650 _ 7 |2 WoSType
|a J
653 2 0 |2 Author
|a fMRI
653 2 0 |2 Author
|a Resting state
653 2 0 |2 Author
|a Meta-analysis
653 2 0 |2 Author
|a Connectivity modeling
653 2 0 |2 Author
|a Right temporo-parietal junction
700 1 _ |0 P:(DE-Juel1)131693
|a Langner, R.
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|a Caspers, S.
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|a Roski, C.
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|a Cieslik, E.C.
|b 4
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|a Zilles, K.
|b 5
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|a Laird, A.R.
|b 6
700 1 _ |0 P:(DE-HGF)0
|a Fox, P. T.
|b 7
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|a Eickhoff, S.B.
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|a 10.1016/j.neuroimage.2012.02.037
|g Vol. 60, p. 2389 - 2398
|p 2389 - 2398
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|t NeuroImage
|v 60
|x 1053-8119
|y 2012
856 7 _ |2 Pubmed Central
|u http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321133
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