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@ARTICLE{Caspers:20245,
author = {Caspers, S. and Schleicher, A. and Bacha-Trams, M. and
Palomero-Gallagher, N. and Amunts, K. and Zilles, K.},
title = {{O}rganization of the {H}uman {I}nferior {P}arietal
{L}obule {B}ased on {R}eceptor {A}rchitectonics},
journal = {Cerebral cortex},
volume = {23},
number = {3},
issn = {1047-3211},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {PreJuSER-20245},
pages = {615-628},
year = {2013},
note = {Record converted from VDB: 12.11.2012},
abstract = {Human inferior parietal lobule (IPL) plays a key role in
various cognitive functions. Its functional diversity,
including attention, language, and action processing, is
reflected by its structural segregation into 7
cytoarchitectonically distinct areas, each with
characteristic connectivity patterns. We hypothesized that
commonalities of the cytoarchitectonic, connectional, and
functional diversity of the IPL should be reflected by a
correlated transmitter receptor-based organization. Since
the function of a cortical area requires a well-tuned
receptor balance, the densities of 15 different receptors
were measured in each IPL area. A hierarchical cluster
analysis of the receptor balance revealed a tripartite
segregation of the IPL into a rostral, middle, and caudal
group. Comparison with other cortical areas showed strong
similarities with Broca's region for all 3 groups, with the
superior parietal cortex for the middle, and with
extrastriate visual areas for the caudal group. Notably,
caudal-most area PGp has a receptor fingerprint very similar
to that of ventral extrastriate visual cortex. We therefore
propose a new organizational model of the human IPL,
consisting of 3 clusters, which corresponds to its known
cytoarchitectonic, connectional, and functional diversity at
the molecular level. This might reflect a general
organizational principle of human IPL, beyond specific
functional domains.},
cin = {INM-2 / INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-1-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems},
pid = {G:(DE-Juel1)FUEK409},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22375016},
UT = {WOS:000316275400012},
doi = {10.1093/cercor/bhs048},
url = {https://juser.fz-juelich.de/record/20245},
}