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@ARTICLE{Kondrat:202703,
      author       = {Kondrat, Svyatoslav and Zimmermann, Olav and Wiechert,
                      Wolfgang and Lieres, Eric von},
      title        = {{T}he effect of composition on {D}iffusion of
                      macromolecules in a crowded environment},
      journal      = {Physical biology},
      volume       = {12},
      number       = {4},
      issn         = {1478-3975},
      address      = {Philadelphia, Pa.},
      publisher    = {IOP Publ.},
      reportid     = {FZJ-2015-04887},
      pages        = {046003 -},
      year         = {2015},
      abstract     = {We study diffusion of macromolecules in a crowded
                      cytoplasm-like environment, focusing on its dependence on
                      composition and its crossover to the anomalous subdiffusion.
                      The crossover and the diffusion itself depend on both the
                      volume fraction and the relative concentration of
                      macromolecules. In accordance with previous theoretical and
                      experimental studies, diffusion slows down when the volume
                      fraction increases. Contrary to expectations, however, the
                      diffusion is also strongly dependent on the molecular
                      composition. The crossover time decreases and diffusion
                      slows down when the smaller macromolecules start to
                      dominate. Interestingly, diffusion is faster in a
                      cytoplasm-like (more polydisperse) system than it is in a
                      two-component system, at comparable packing fractions, or
                      even when the cytoplasm packing fraction is larger.},
      cin          = {IBG-1 / JSC},
      ddc          = {530},
      cid          = {I:(DE-Juel1)IBG-1-20101118 / I:(DE-Juel1)JSC-20090406},
      pnm          = {511 - Computational Science and Mathematical Methods
                      (POF3-511) / 581 - Biotechnology (POF3-581)},
      pid          = {G:(DE-HGF)POF3-511 / G:(DE-HGF)POF3-581},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000361837200011},
      doi          = {10.1088/1478-3975/12/4/046003},
      url          = {https://juser.fz-juelich.de/record/202703},
}