%0 Journal Article %A Formighieri, C. %A Franck, F. %A Bassi, R. %T Regulation of the pigment optical density of an algal culture: filling the gap between photosynthetic productivity in the laboratory and in mass culture %J Journal of biotechnology %V 162 %@ 0168-1656 %C Amsterdam [u.a.] %I Elsevier Science %M PreJuSER-20338 %P 115 - 123 %D 2012 %Z Record converted from VDB: 12.11.2012 %X An increasing number of investors is looking at algae as a viable source of biofuels, beside cultivation for human/animal feeding or to extract high-value chemicals and pharmaceuticals. However, present biomass productivities are far below theoretical estimations implying that a large part of the available photosynthetically active radiation is not used in photosynthesis. Light utilisation inefficiency and rapid light attenuation within a mass culture due to high pigment optical density of wild type strains have been proposed as major limiting factors reducing solar-to-biomass conversion efficiency. Analysis of growth yields of mutants with reduced light-harvesting antennae and/or reduced overall pigment concentration per cell, generated by either mutagenesis or genetic engineering, could help understanding limiting factors for biomass accumulation in photobioreactor. Meanwhile, studies on photo-acclimation can provide additional information on the average status of algal cells in a photobioreactor to be used in modelling-based predictions. Identifying limiting factors in solar-to-biomass conversion efficiency is the first step for planning strategies of genetic improvement and domestication of algae to finally fill the gap between theoretical and industrial photosynthetic productivity. %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:22426090 %U <Go to ISI:>//WOS:000311019700015 %R 10.1016/j.jbiotec.2012.02.021 %U https://juser.fz-juelich.de/record/20338