Home > Publications database > Neural correlates of reactive aggression in children with attention-deficit/hyperactivity disorder and comorbid disruptive behaviour disorders > print

001     203446
005     20210129220359.0
024 7 _ |a 10.1111/acps.12475
|2 doi
024 7 _ |a 0001-690x
|2 ISSN
024 7 _ |a 0065-1591
|2 ISSN
024 7 _ |a 1600-5473
|2 ISSN
024 7 _ |a WOS:000372908000007
|2 WOS
024 7 _ |a altmetric:4421064
|2 altmetric
024 7 _ |a pmid:26292852
|2 pmid
037 _ _ |a FZJ-2015-05382
082 _ _ |a 610
100 1 _ |a Bubenzer-Busch, S.
|0 P:(DE-HGF)0
|b 0
245 _ _ |a Neural correlates of reactive aggression in children with attention-deficit/hyperactivity disorder and comorbid disruptive behaviour disorders
260 _ _ |a Oxford [u. a.]
|c 2016
|b Wiley-Blackwell
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1460457871_4972
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
520 _ _ |a ObjectiveAttention deficit hyperactivity disorder (ADHD) is often linked with impulsive and aggressive behaviour, indexed by high comorbidity rates between ADHD and disruptive behaviour disorders (DBD). The present study aimed to investigate underlying neural activity of reactive aggression in children with ADHD and comorbid DBD using functional neuroimaging techniques (fMRI).MethodEighteen boys with ADHD (age 9–14 years, 10 subjects with comorbid DBD) and 18 healthy controls were administered a modified fMRI-based version of the ‘Point Subtraction Aggression Game’ to elicit reactive aggressive behaviour. Trials consisted of an ‘aggression phase’ (punishment for a fictitious opponent) and an ‘outcome phase’ (presentation of the trial outcome).ResultsDuring the aggression phase, higher aggressive responses of control children were accompanied by higher activation of the ventral anterior cingulate cortex and the temporoparietal junction. Patients displayed inverted results. During the outcome phase, comparison between groups and conditions showed differential activation in the dorsal striatum and bilateral insular when subjects gained points. Losing points was accompanied by differential activation of regions belonging to the insula and the middle temporal sulcus.ConclusionData support the hypothesis that deficient inhibitory control mechanisms are related to increased impulsive aggressive behaviour in young people with ADHD and comorbid DBD.
536 _ _ |a 571 - Connectivity and Activity (POF3-571)
|0 G:(DE-HGF)POF3-571
|c POF3-571
|f POF III
|x 0
588 _ _ |a Dataset connected to CrossRef
700 1 _ |a Herpertz-Dahlmann, B.
|0 P:(DE-HGF)0
|b 1
700 1 _ |a Kuzmanovic, B.
|0 P:(DE-Juel1)144165
|b 2
|u fzj
700 1 _ |a Gaber, T. J.
|0 P:(DE-HGF)0
|b 3
700 1 _ |a Helmbold, K.
|0 P:(DE-HGF)0
|b 4
700 1 _ |a Ullisch, M. G.
|0 P:(DE-HGF)0
|b 5
700 1 _ |a Baurmann, D.
|0 P:(DE-HGF)0
|b 6
700 1 _ |a Eickhoff, Simon
|0 P:(DE-Juel1)131678
|b 7
|u fzj
700 1 _ |a Fink, G. R.
|0 P:(DE-Juel1)131720
|b 8
|u fzj
700 1 _ |a Zepf, F. D.
|0 P:(DE-HGF)0
|b 9
|e Corresponding author
773 _ _ |a 10.1111/acps.12475
|g p. n/a - n/a
|0 PERI:(DE-600)2005703-9
|n 4
|p 310-323
|t Acta psychiatrica Scandinavica
|v 133
|y 2016
|x 0001-690X
909 C O |o oai:juser.fz-juelich.de:203446
|p VDB
910 1 _ |a Forschungszentrum Jülich GmbH
|0 I:(DE-588b)5008462-8
|k FZJ
|b 2
|6 P:(DE-Juel1)144165
910 1 _ |a Forschungszentrum Jülich GmbH
|0 I:(DE-588b)5008462-8
|k FZJ
|b 7
|6 P:(DE-Juel1)131678
910 1 _ |a Forschungszentrum Jülich GmbH
|0 I:(DE-588b)5008462-8
|k FZJ
|b 8
|6 P:(DE-Juel1)131720
913 1 _ |a DE-HGF
|b Key Technologies
|l Decoding the Human Brain
|1 G:(DE-HGF)POF3-570
|0 G:(DE-HGF)POF3-571
|2 G:(DE-HGF)POF3-500
|v Connectivity and Activity
|x 0
|4 G:(DE-HGF)POF
|3 G:(DE-HGF)POF3
914 1 _ |y 2015
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b ACTA PSYCHIAT SCAND : 2014
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0310
|2 StatID
|b NCBI Molecular Biology Database
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Thomson Reuters Master Journal List
915 _ _ |a WoS
|0 StatID:(DE-HGF)0110
|2 StatID
|b Science Citation Index
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
915 _ _ |a WoS
|0 StatID:(DE-HGF)0111
|2 StatID
|b Science Citation Index Expanded
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0130
|2 StatID
|b Social Sciences Citation Index
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1020
|2 StatID
|b Current Contents - Social and Behavioral Sciences
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1030
|2 StatID
|b Current Contents - Life Sciences
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
915 _ _ |a IF >= 5
|0 StatID:(DE-HGF)9905
|2 StatID
|b ACTA PSYCHIAT SCAND : 2014
920 1 _ |0 I:(DE-Juel1)INM-1-20090406
|k INM-1
|l Strukturelle und funktionelle Organisation des Gehirns
|x 0
920 1 _ |0 I:(DE-Juel1)INM-3-20090406
|k INM-3
|l Kognitive Neurowissenschaften
|x 1
920 1 _ |0 I:(DE-Juel1)INM-8-20090406
|k INM-8
|l Ethik in den Neurowissenschaften
|x 2
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-Juel1)INM-1-20090406
980 _ _ |a I:(DE-Juel1)INM-3-20090406
980 _ _ |a I:(DE-Juel1)INM-8-20090406
980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)INM-3-20090406
981 _ _ |a I:(DE-Juel1)INM-8-20090406

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21