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000020486 084__ $$2WoS$$aClinical Neurology
000020486 084__ $$2WoS$$aPsychiatry
000020486 1001_ $$0P:(DE-HGF)0$$aLehnhardt, F.G.$$b0
000020486 245__ $$aDas psychosoziale Funktionsniveau spätdiagnostizierter PatientInnen mit hochfunktionalem Autismus im Erwachsenenalter.
000020486 260__ $$aStuttgart [u.a.]$$bThieme$$c2012
000020486 300__ $$a88 - 97
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000020486 440_0 $$018781$$aFortschritte der Neurologie Psychiatrie$$v80$$x0720-4299$$y2
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000020486 520__ $$aThe first time diagnosis of autism spectrum disorder (ASD) after passing childhood and adolescence is still considered a rare event. However, in recent years an increasing demand for diagnostic clarifications with suspected ASD in adulthood challenges this view. There is insufficient knowledge about the neuropsychological characterisation and psychosocial outcome of this adult subgroup in the autistic spectrum.To determine the psychosocial functioning (living status, partnerships, level of education, psychiatric history) of adult patients with late diagnosed ASD.In a retrospective study, a chart review was conducted on 178 consecutively diagnosed individuals at a specialised outpatient clinic for adults with ASD. Global ratings of psychosocial functioning, assessment of psychiatric history and neuropsychological and psychopathological investigations were evaluated.The majority of patients (92 %) diagnosed with ASD suffered from high-functioning autism (HFA)/Asperger syndrome (AS) according to the criteria of ICD-10 (F84.5). The gender ratio was 2:1 favouring males. Mean age at diagnosis (34.1 ± 9.5 years), general intelligence (HAWIE-R, global-IQ 115 ± 20) and self-rated autistic symptoms (autism spectrum quotient [AQ] 39 ± 6) were not discriminative to gender. The psychiatric history revealed a lifetime consultation rate of 78 %, most frequently with depression (50 %). The self-report instrument Beck depression inventory (BDI) identified 30 % of individuals presenting with depressive symptoms in clinical relevant intensity (BDI > 17). Achievement of an independent living status was reported by 68 % of individuals, 58 % reported about current or past intimate partnerships and almost two-thirds of the patients had achieved a higher educational status.The majority of ASD diagnosed late in lifetime turned out to be HFA/AS, presenting with high psychosocial adjustment with regard to independent living, educational status and partnerships. The high level of global intelligence supports the hypothesis of cognitively compensated autistic disturbances leading to the diagnosis comparably late in lifetime. The lifetime rate of psychiatric consultations is high, reflecting the importance to consider a diagnosis of ASD even late in life.
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000020486 650_2 $$2MeSH$$aAdult
000020486 650_2 $$2MeSH$$aAge Factors
000020486 650_2 $$2MeSH$$aAsperger Syndrome: psychology
000020486 650_2 $$2MeSH$$aChild
000020486 650_2 $$2MeSH$$aChild Development Disorders, Pervasive: epidemiology
000020486 650_2 $$2MeSH$$aChild Development Disorders, Pervasive: psychology
000020486 650_2 $$2MeSH$$aComorbidity
000020486 650_2 $$2MeSH$$aDepression: complications
000020486 650_2 $$2MeSH$$aDepression: psychology
000020486 650_2 $$2MeSH$$aEducational Status
000020486 650_2 $$2MeSH$$aFemale
000020486 650_2 $$2MeSH$$aHumans
000020486 650_2 $$2MeSH$$aInternational Classification of Diseases
000020486 650_2 $$2MeSH$$aInterpersonal Relations
000020486 650_2 $$2MeSH$$aMale
000020486 650_2 $$2MeSH$$aMental Disorders: etiology
000020486 650_2 $$2MeSH$$aMental Disorders: psychology
000020486 650_2 $$2MeSH$$aMiddle Aged
000020486 650_2 $$2MeSH$$aNeuropsychological Tests
000020486 650_2 $$2MeSH$$aOutpatients
000020486 650_2 $$2MeSH$$aPsychiatric Status Rating Scales
000020486 650_2 $$2MeSH$$aRetrospective Studies
000020486 650_2 $$2MeSH$$aSex Factors
000020486 650_2 $$2MeSH$$aSocial Behavior
000020486 650_2 $$2MeSH$$aYoung Adult
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000020486 65320 $$2Author$$aAsperger syndrome
000020486 65320 $$2Author$$aadulthood
000020486 65320 $$2Author$$adiagnosis late in life
000020486 65320 $$2Author$$apsychosocial functioning
000020486 7001_ $$0P:(DE-HGF)0$$aGawronski, A.$$b1
000020486 7001_ $$0P:(DE-HGF)0$$aVolpert, K.$$b2
000020486 7001_ $$0P:(DE-HGF)0$$aSchilbach, L.$$b3
000020486 7001_ $$0P:(DE-HGF)0$$aTepest, R.$$b4
000020486 7001_ $$0P:(DE-HGF)0$$aHuff, W.$$b5
000020486 7001_ $$0P:(DE-Juel1)VDB1715$$aVogeley, K.$$b6$$uFZJ
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