000021063 001__ 21063 000021063 005__ 20190625110524.0 000021063 0247_ $$2pmid$$apmid:22487254 000021063 0247_ $$2DOI$$a10.1111/j.1365-313X.2012.05021.x 000021063 0247_ $$2WOS$$aWOS:000307169600012 000021063 0247_ $$2altmetric$$aaltmetric:789288 000021063 037__ $$aPreJuSER-21063 000021063 041__ $$aeng 000021063 082__ $$a580 000021063 084__ $$2WoS$$aPlant Sciences 000021063 1001_ $$0P:(DE-HGF)0$$aMeyer, R.C.$$b0 000021063 245__ $$aHeterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids 000021063 260__ $$aOxford [u.a.]$$bWiley-Blackwell$$c2012 000021063 300__ $$a669 - 683 000021063 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article 000021063 3367_ $$2DataCite$$aOutput Types/Journal article 000021063 3367_ $$00$$2EndNote$$aJournal Article 000021063 3367_ $$2BibTeX$$aARTICLE 000021063 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000021063 3367_ $$2DRIVER$$aarticle 000021063 440_0 $$015001$$aPlant Journal$$v71$$x0960-7412$$y4 000021063 500__ $$aThis work was supported by research grants from the Deutsche Forschungsgemeinschaft (SPP1149), the European Commission Framework Programme 6 Integrated Project: AGRON-OMICS (LSHG-CT 2006-037704), the German Ministry for Education and Research (GoFORSYS, GABI-OIL 0315053G) and the Max Planck Society. 000021063 520__ $$aHeterosis-associated cellular and molecular processes were analyzed in seeds and seedlings of Arabidopsis thaliana accessions Col-0 and C24 and their heterotic hybrids. Microscopic examination revealed no advantages in terms of hybrid mature embryo organ sizes or cell numbers. Increased cotyledon sizes were detectable 4 days after sowing. Growth heterosis results from elevated cell sizes and numbers, and is well established at 10 days after sowing. The relative growth rates of hybrid seedlings were most enhanced between 3 and 4 days after sowing. Global metabolite profiling and targeted fatty acid analysis revealed maternal inheritance patterns for a large proportion of metabolites in the very early stages. During developmental progression, the distribution shifts to dominant, intermediate and heterotic patterns, with most changes occurring between 4 and 6 days after sowing. The highest incidence of heterotic patterns coincides with establishment of size differences at 4 days after sowing. In contrast, overall transcript patterns at 4, 6 and 10 days after sowing are characterized by intermediate to dominant patterns, with parental transcript levels showing the largest differences. Overall, the results suggest that, during early developmental stages, intermediate gene expression and higher metabolic activity in the hybrids compared to the parents lead to better resource efficiency, and therefore enhanced performance in the hybrids. 000021063 536__ $$0G:(DE-Juel1)FUEK407$$2G:(DE-HGF)$$aTerrestrische Umwelt$$cP24$$x0 000021063 588__ $$aDataset connected to Web of Science, Pubmed 000021063 65320 $$2Author$$aheterosis 000021063 65320 $$2Author$$aseedlings 000021063 65320 $$2Author$$ametabolite profiling 000021063 65320 $$2Author$$atranscript profiling 000021063 65320 $$2Author$$amorphological analysis 000021063 65320 $$2Author$$aArabidopsis thaliana 000021063 65320 $$2Author$$abiomass 000021063 650_7 $$2WoSType$$aJ 000021063 7001_ $$0P:(DE-HGF)0$$aWitucka-Wall, H.$$b1 000021063 7001_ $$0P:(DE-Juel1)129280$$aBecher, M.$$b2$$uFZJ 000021063 7001_ $$0P:(DE-HGF)0$$aBlacha, A.$$b3 000021063 7001_ $$0P:(DE-HGF)0$$aBoudichevskaia, A.$$b4 000021063 7001_ $$0P:(DE-HGF)0$$aDörmann, P.$$b5 000021063 7001_ $$0P:(DE-HGF)0$$aFiehn, O.$$b6 000021063 7001_ $$0P:(DE-HGF)0$$aFriedel, S.$$b7 000021063 7001_ $$0P:(DE-HGF)0$$avon Korff, M.$$b8 000021063 7001_ $$0P:(DE-HGF)0$$aLisec, J.$$b9 000021063 7001_ $$0P:(DE-HGF)0$$aMelzer, M.$$b10 000021063 7001_ $$0P:(DE-HGF)0$$aRepsilber, D.$$b11 000021063 7001_ $$0P:(DE-HGF)0$$aSchmidt, R.$$b12 000021063 7001_ $$0P:(DE-HGF)0$$aScholz, M.$$b13 000021063 7001_ $$0P:(DE-HGF)0$$aSelbig, J.$$b14 000021063 7001_ $$0P:(DE-HGF)0$$aWillmitzer, L.$$b15 000021063 7001_ $$0P:(DE-Juel1)VDB90356$$aAltmann, T.$$b16$$uFZJ 000021063 773__ $$0PERI:(DE-600)2020961-7$$a10.1111/j.1365-313X.2012.05021.x$$gVol. 71, p. 669 - 683$$p669 - 683$$q71<669 - 683$$tThe @plant journal$$v71$$x0960-7412$$y2012 000021063 8567_ $$uhttp://dx.doi.org/10.1111/j.1365-313X.2012.05021.x 000021063 909CO $$ooai:juser.fz-juelich.de:21063$$pVDB 000021063 915__ $$0StatID:(DE-HGF)0010$$2StatID$$aJCR/ISI refereed 000021063 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR 000021063 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index 000021063 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000021063 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000021063 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000021063 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000021063 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000021063 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000021063 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences 000021063 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews 000021063 915__ $$0StatID:(DE-HGF)1060$$2StatID$$aDBCoverage$$bCurrent Contents - Agriculture, Biology and Environmental Sciences 000021063 9141_ $$y2012 000021063 9131_ $$0G:(DE-Juel1)FUEK407$$1G:(DE-HGF)POF2-240$$2G:(DE-HGF)POF2-200$$aDE-HGF$$bErde und Umwelt$$kP24$$lTerrestrische Umwelt$$vTerrestrische Umwelt$$x0 000021063 9132_ $$0G:(DE-HGF)POF3-582$$1G:(DE-HGF)POF3-580$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lKey Technologies for the Bioeconomy$$vPlant Science$$x0 000021063 9201_ $$0I:(DE-Juel1)IBG-2-20101118$$gIBG$$kIBG-2$$lPflanzenwissenschaften$$x0 000021063 970__ $$aVDB:(DE-Juel1)136855 000021063 980__ $$aVDB 000021063 980__ $$aConvertedRecord 000021063 980__ $$ajournal 000021063 980__ $$aI:(DE-Juel1)IBG-2-20101118 000021063 980__ $$aUNRESTRICTED