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@ARTICLE{Dovern:21471,
      author       = {Dovern, A. and Fink, G.R. and Fromme, A. and Wohlschlaeger,
                      A. and Weiss, P.H.},
      title        = {{I}ntrinsic network connectivity reflects consistency of
                      synesthetic experiences},
      journal      = {The journal of neuroscience},
      volume       = {32},
      issn         = {0270-6474},
      address      = {Washington, DC},
      publisher    = {Soc.},
      reportid     = {PreJuSER-21471},
      pages        = {7614 - 7621},
      year         = {2012},
      note         = {This work was supported by Grant 8762754 of the Kommission
                      fuer Klinische Forschung at the Klinikum Rechts der Isar (to
                      V. R.). We are grateful to our subjects and our colleagues
                      at the Institute of Neurocience and Medicine, Research
                      Centre Julich.},
      abstract     = {Studying cognitive processes underlying synesthesia, a
                      condition in which stimulation of one sensory modality
                      automatically leads to abnormal additional sensory
                      perception, allows insights into the neural mechanisms of
                      normal and abnormal cross-modal sensory processing.
                      Consistent with the notion that synesthesia results from
                      hyperconnectivity, functional connectivity analysis
                      (adopting independent component analysis and seed-based
                      correlation analysis) of resting-state functional magnetic
                      resonance imaging data of 12 grapheme-color synesthetes and
                      12 nonsynesthetic control subjects revealed, in addition to
                      increased intranetwork connectivity, both a global and a
                      specific (medial and lateral visual networks to a right
                      frontoparietal network) increase of intrinsic internetwork
                      connectivity in grapheme-color synesthesia. Moreover, this
                      increased intrinsic network connectivity reflected the
                      strength of synesthetic experiences. These findings
                      constitute the first direct evidence of increased functional
                      network connectivity in synesthesia. In addition to this
                      significant contribution to the understanding of the neural
                      mechanisms of synesthesia, our results have important
                      general implications. In combination with data derived from
                      clinical populations, our data strongly suggest that altered
                      differences in intrinsic network connectivity are directly
                      related to the phenomenology of human experiences.},
      keywords     = {Adult / Analysis of Variance / Auditory Perception:
                      physiology / Brain: blood supply / Brain: pathology / Brain
                      Mapping / Color Perception / Female / Humans / Image
                      Processing, Computer-Assisted / Magnetic Resonance Imaging /
                      Male / Neural Pathways: blood supply / Neural Pathways:
                      pathology / Oxygen: blood / Perceptual Disorders: pathology
                      / Phonetics / Regression Analysis / Rest / Young Adult /
                      Oxygen (NLM Chemicals) / J (WoSType)},
      cin          = {INM-3},
      ddc          = {590},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
                      89572 - (Dys-)function and Plasticity (POF2-89572)},
      pid          = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89572},
      shelfmark    = {Neurosciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22649240},
      UT           = {WOS:000304627100020},
      doi          = {10.1523/JNEUROSCI.5401-11.2012},
      url          = {https://juser.fz-juelich.de/record/21471},
}