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@ARTICLE{Kaufhold:21501,
      author       = {Kaufhold, S. and Plötze, M. and Klinkenberg, M. and
                      Dohrmann, R. and Siegesmund, S.},
      title        = {{D}ensity and porosity of bentonites},
      journal      = {Journal of porous materials},
      volume       = {20},
      issn         = {1380-2224},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V},
      reportid     = {PreJuSER-21501},
      pages        = {191-208},
      year         = {2013},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Chronic obstructive pulmonary disease (COPD) is a growing
                      cause of morbidity and mortality worldwide, and accurate
                      estimates of the prevalence of this disease are needed to
                      anticipate the future burden of COPD, target key risk
                      factors, and plan for providing COPD-related health
                      services. We aimed to measure the prevalence of COPD and its
                      risk factors and investigate variation across countries by
                      age, sex, and smoking status.Participants from 12 sites
                      (n=9425) completed postbronchodilator spirometry testing
                      plus questionnaires about respiratory symptoms, health
                      status, and exposure to COPD risk factors. COPD prevalence
                      estimates based on the Global Initiative for Chronic
                      Obstructive Lung Disease staging criteria were adjusted for
                      the target population. Logistic regression was used to
                      estimate adjusted odds ratios (ORs) for COPD associated with
                      10-year age increments and 10-pack-year (defined as the
                      number of cigarettes smoked per day divided by 20 and
                      multiplied by the number of years that the participant
                      smoked) increments. Meta-analyses provided pooled estimates
                      for these risk factors.The prevalence of stage II or higher
                      COPD was $10.1\%$ (SE 4.8) overall, $11.8\%$ (7.9) for men,
                      and $8.5\%$ (5.8) for women. The ORs for 10-year age
                      increments were much the same across sites and for women and
                      men. The overall pooled estimate was 1.94 $(95\%$ CI
                      1.80-2.10) per 10-year increment. Site-specific pack-year
                      ORs varied significantly in women (pooled OR=1.28, $95\%$ CI
                      1.15-1.42, p=0.012), but not in men (1.16, 1.12-1.21,
                      p=0.743).This worldwide study showed higher levels and more
                      advanced staging of spirometrically confirmed COPD than have
                      typically been reported. However, although age and smoking
                      are strong contributors to COPD, they do not fully explain
                      variations in disease prevalence-other factors also seem to
                      be important. Although smoking cessation is becoming an
                      increasingly urgent objective for an ageing worldwide
                      population, a better understanding of other factors that
                      contribute to COPD is crucial to assist local public-health
                      officials in developing the best possible primary and
                      secondary prevention policies for their regions.},
      keywords     = {Adult / Age Distribution / Aged / Female / Humans /
                      Logistic Models / Male / Middle Aged / Multicenter Studies
                      as Topic / Population Surveillance: methods / Prevalence /
                      Pulmonary Disease, Chronic Obstructive: epidemiology /
                      Pulmonary Disease, Chronic Obstructive: etiology /
                      Questionnaires / Risk Factors / Sex Distribution / Smoking:
                      adverse effects / Smoking: epidemiology},
      cin          = {IEK-6},
      ddc          = {670},
      cid          = {I:(DE-Juel1)IEK-6-20101013},
      pnm          = {Nukleare Sicherheitsforschung},
      pid          = {G:(DE-Juel1)FUEK404},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:17765523},
      UT           = {WOS:000312933400022},
      doi          = {10.1007/s10934-012-9589-7},
      url          = {https://juser.fz-juelich.de/record/21501},
}