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001     21501
005     20240712084608.0
024 7 _ |2 pmid
|a pmid:17765523
024 7 _ |2 DOI
|a 10.1007/s10934-012-9589-7
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037 _ _ |a PreJuSER-21501
041 _ _ |a eng
082 _ _ |a 670
100 1 _ |a Kaufhold, S.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Density and porosity of bentonites
260 _ _ |a Dordrecht [u.a.]
|b Springer Science + Business Media B.V
|c 2013
300 _ _ |a 191-208
336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a article
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440 _ 0 |a Journal of Porous Materials
|x 1380-2224
|0 3724
|v 20
500 _ _ |3 POF3_Assignment on 2016-02-29
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide, and accurate estimates of the prevalence of this disease are needed to anticipate the future burden of COPD, target key risk factors, and plan for providing COPD-related health services. We aimed to measure the prevalence of COPD and its risk factors and investigate variation across countries by age, sex, and smoking status.Participants from 12 sites (n=9425) completed postbronchodilator spirometry testing plus questionnaires about respiratory symptoms, health status, and exposure to COPD risk factors. COPD prevalence estimates based on the Global Initiative for Chronic Obstructive Lung Disease staging criteria were adjusted for the target population. Logistic regression was used to estimate adjusted odds ratios (ORs) for COPD associated with 10-year age increments and 10-pack-year (defined as the number of cigarettes smoked per day divided by 20 and multiplied by the number of years that the participant smoked) increments. Meta-analyses provided pooled estimates for these risk factors.The prevalence of stage II or higher COPD was 10.1% (SE 4.8) overall, 11.8% (7.9) for men, and 8.5% (5.8) for women. The ORs for 10-year age increments were much the same across sites and for women and men. The overall pooled estimate was 1.94 (95% CI 1.80-2.10) per 10-year increment. Site-specific pack-year ORs varied significantly in women (pooled OR=1.28, 95% CI 1.15-1.42, p=0.012), but not in men (1.16, 1.12-1.21, p=0.743).This worldwide study showed higher levels and more advanced staging of spirometrically confirmed COPD than have typically been reported. However, although age and smoking are strong contributors to COPD, they do not fully explain variations in disease prevalence-other factors also seem to be important. Although smoking cessation is becoming an increasingly urgent objective for an ageing worldwide population, a better understanding of other factors that contribute to COPD is crucial to assist local public-health officials in developing the best possible primary and secondary prevention policies for their regions.
536 _ _ |a Nukleare Sicherheitsforschung
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588 _ _ |a Dataset connected to Pubmed
650 _ 2 |2 MeSH
|a Adult
650 _ 2 |2 MeSH
|a Age Distribution
650 _ 2 |2 MeSH
|a Aged
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Logistic Models
650 _ 2 |2 MeSH
|a Male
650 _ 2 |2 MeSH
|a Middle Aged
650 _ 2 |2 MeSH
|a Multicenter Studies as Topic
650 _ 2 |2 MeSH
|a Population Surveillance: methods
650 _ 2 |2 MeSH
|a Prevalence
650 _ 2 |2 MeSH
|a Pulmonary Disease, Chronic Obstructive: epidemiology
650 _ 2 |2 MeSH
|a Pulmonary Disease, Chronic Obstructive: etiology
650 _ 2 |2 MeSH
|a Questionnaires
650 _ 2 |2 MeSH
|a Risk Factors
650 _ 2 |2 MeSH
|a Sex Distribution
650 _ 2 |2 MeSH
|a Smoking: adverse effects
650 _ 2 |2 MeSH
|a Smoking: epidemiology
700 1 _ |a Plötze, M.
|b 1
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700 1 _ |a Klinkenberg, M.
|b 2
|u FZJ
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700 1 _ |a Dohrmann, R.
|b 3
|0 P:(DE-HGF)0
700 1 _ |a Siegesmund, S.
|b 4
|0 P:(DE-HGF)0
773 _ _ |a 10.1007/s10934-012-9589-7
|0 PERI:(DE-600)2007476-1
|y 2013
|t Journal of porous materials
|x 1380-2224
|p 191-208
|v 20
856 7 _ |u http://dx.doi.org/10.1007/s10934-012-9589-7
856 4 _ |u https://juser.fz-juelich.de/record/21501/files/FZJ-21501.pdf
|z Published final document.
|y Restricted
909 C O |o oai:juser.fz-juelich.de:21501
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914 1 _ |y 2013
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