TY  - JOUR
AU  - Bensmail, D.
AU  - Sarfeld, A.S.
AU  - Ameli, M.
AU  - Fink, G.R.
AU  - Nowak, D.A.
TI  - Arbitrary visuomotor mapping in the grip-lift task: Dissociation of performance deficits in right and left middle cerebral artery stroke
JO  - Neuroscience
VL  - 210
SN  - 0306-4522
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - PreJuSER-22233
SP  - 128 - 136
PY  - 2012
N1  - This study was supported by a grant of the Deutsche Forschungsgemeinschaft (no 73715-1). Djamel Bensmail was supported by grants of Fondation Garches, SOFMER-IPSEN, Assistance Publique-Hopitaux de Paris, Allergan, and Medtronic.
AB  - The ability to rapidly establish a memory link between arbitrary sensory cues and goal-directed movements is part of our daily motor repertoire. It is unknown if this ability is affected by middle cerebral artery stroke. Eighteen right-handed subjects with a first unilateral middle cerebral artery stroke were studied while performing a precision grip to lift objects of different weights. In a "no cue" condition, a noninformative neutral visual stimulus was presented before each lift, thereby not allowing any judgment about the object weight. In a "cue" condition arbitrary color cues provided advance information about the weight to be lifted in the subsequent trial. Subjects performed both conditions with either hand. During "no cue" trials subjects scaled their grip force according to the weight of the preceding lift, irrespective of the hand performing the lift or the hemisphere affected. The presentation of color cues allowed patients with right hemispheric stroke, but not those with left hemispheric stroke, to scale their grip force according to the weight in the upcoming lift when lifting the weight with the unaffected hand. Color cues did not allow for a predictive scaling of grip force according to the weight of the object to be lifted when lifting with the affected hand, irrespective of the affected hemisphere. These data imply that the ability of visuomotor mapping in the grip-lift task is selectively impaired in the affected hand after right middle cerebral artery stroke, but in both hands after left middle cerebral artery stroke.
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Brain: physiopathology
KW  - Cues
KW  - Female
KW  - Functional Laterality: physiology
KW  - Hand Strength: physiology
KW  - Humans
KW  - Infarction, Middle Cerebral Artery: complications
KW  - Infarction, Middle Cerebral Artery: physiopathology
KW  - Male
KW  - Middle Aged
KW  - Psychomotor Performance: physiology
KW  - Weight Perception: physiology
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:22441039
UR  - <Go to ISI:>//WOS:000304730000012
DO  - DOI:10.1016/j.neuroscience.2012.03.015
UR  - https://juser.fz-juelich.de/record/22233
ER  -