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@ARTICLE{Cieslik:22526,
author = {Cieslik, E.C. and Zilles, K. and Caspers, S. and Roski, C.
and Kellermann, T.S. and Jakobs, O. and Langner, R. and
Laird, A.R. and Fox, P.T. and Eickhoff, S.B.},
title = {{I}s there one {DLPFC} in cognitive action control?
{E}vidence for heterogeneity from co-activation-based
parcellation},
journal = {Cerebral cortex},
volume = {23},
number = {11},
issn = {1047-3211},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {PreJuSER-22526},
pages = {2677-2689},
year = {2012},
note = {Record converted from VDB: 12.11.2012},
abstract = {The dorsolateral prefrontal cortex (DLPFC) has consistently
been implicated in cognitive control of motor behavior.
There is, however, considerable variability in the exact
location and extension of these activations across
functional magnetic resonance imaging (fMRI) experiments.
This poses the question of whether this variability reflects
sampling error and spatial uncertainty in fMRI experiments
or structural and functional heterogeneity of this region.
This study shows that the right DLPFC as observed in 4
different experiments tapping executive action control may
be subdivided into 2 distinct subregions-an anterior-ventral
and a posterior-dorsal one -based on their whole-brain
co-activation patterns across neuroimaging studies.
Investigation of task-dependent and task-independent
connectivity revealed both clusters to be involved in
distinct neural networks. The posterior subregion showed
increased connectivity with bilateral intraparietal sulci,
whereas the anterior subregion showed increased connectivity
with the anterior cingulate cortex. Functional
characterization with quantitative forward and reverse
inferences revealed the anterior network to be more strongly
associated with attention and action inhibition processes,
whereas the posterior network was more strongly related to
action execution and working memory. The present data
provide evidence that cognitive action control in the right
DLPFC may rely on differentiable neural networks and
cognitive functions.},
cin = {INM-1 / INM-2},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406 / I:(DE-Juel1)INM-2-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems},
pid = {G:(DE-Juel1)FUEK409},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22918987},
UT = {WOS:000325761100015},
doi = {10.1093/cercor/bhs256},
url = {https://juser.fz-juelich.de/record/22526},
}