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@ARTICLE{Ramage:22554,
      author       = {Ramage, A.E. and Laird, A.R. and Eickhoff, S.B. and
                      Acheson, A. and Peterson, A.L. and Williamson, D.E. and
                      Teich, M.J. and Fox, P.T.},
      title        = {{A} coordinate-based meta-analytic model of trauma
                      processing in posttraumatic stress disorder},
      journal      = {Human brain mapping},
      volume       = {34},
      number       = {12},
      issn         = {1065-9471},
      address      = {New York, NY},
      publisher    = {Wiley-Liss},
      reportid     = {PreJuSER-22554},
      pages        = {3392–3399},
      year         = {2013},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Posttraumatic stress disorder (PTSD) has a well-defined set
                      of symptoms that can be elicited during traumatic imagery
                      tasks. For this reason, trauma imagery tasks are often
                      employed in functional neuroimaging studies. Here,
                      coordinate-based meta-analysis (CBM) was used to pool eight
                      studies applying traumatic imagery tasks to identify sites
                      of task-induced activation in 170 PTSD patients and 104
                      healthy controls. In this way, right anterior cingulate
                      (ACC), right posterior cingulate (PCC), and left precuneus
                      (Pcun) were identified as regions uniquely active in PTSD
                      patients relative to healthy controls. To further
                      characterize these regions, their normal interactions, and
                      their typical functional roles, meta-analytic connectivity
                      modeling (MACM) with behavioral filtering was applied. MACM
                      indicated that the PCC and Pcun regions were frequently
                      co-active and associated with processing of cognitive
                      information, particularly in explicit memory tasks.
                      Emotional processing was particularly associated with
                      co-activity of the ACC and PCC, as mediated by the thalamus.
                      By narrowing the regions of interest to those commonly
                      active across multiple studies (using CBM) and developing a
                      priori hypotheses about directed probabilistic dependencies
                      amongst these regions, this proposed model-when applied in
                      the context of graphical and causal modeling-should improve
                      model fit and thereby increase statistical power for
                      detecting differences between subject groups and between
                      treatments in neuroimaging studies of PTSD. Hum Brain Mapp,
                      2012. © 2012 Wiley Periodicals, Inc.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22936519},
      UT           = {WOS:000326068700022},
      doi          = {10.1002/hbm.22155},
      url          = {https://juser.fz-juelich.de/record/22554},
}