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@ARTICLE{Mller:22747,
      author       = {Müller, V.I. and Kellermann, T.S. and Seligman, S.C. and
                      Turetsky, B.I. and Eickhoff, S.B.},
      title        = {{M}odulation of affective face processing deficits in
                      schizophrenia by congruent emotional sounds},
      journal      = {Social cognitive and affective neuroscience},
      volume       = {9},
      number       = {4},
      issn         = {1749-5016},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {PreJuSER-22747},
      pages        = {436-444},
      year         = {2014},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Schizophrenia is a psychiatric disorder resulting in
                      prominent impairments in social functioning. Thus, clinical
                      research has focused on underlying deficits of emotion
                      processing and their linkage to specific symptoms and
                      neurobiological dysfunctions. Although there is substantial
                      research investigating impairments in unimodal affect
                      recognition, studies in schizophrenia exploring crossmodal
                      emotion processing are rare. Therefore, event-related
                      potentials were measured in 15 patients with schizophrenia
                      and 15 healthy controls while rating the expression of
                      happy, fearful and neutral faces and concurrently being
                      distracted by emotional or neutral sounds. Compared with
                      controls, patients with schizophrenia revealed significantly
                      decreased P1 and increased P2 amplitudes in response to all
                      faces, independent of emotion or concurrent sound. Analyzing
                      these effects with regard to audiovisual (in)congruence
                      revealed that P1 amplitudes in patients were only reduced in
                      response to emotionally incongruent stimulus pairs, whereas
                      similar amplitudes between groups could be observed for
                      congruent conditions. Correlation analyses revealed a
                      significant negative correlation between general symptom
                      severity (Brief Psychiatric Rating Scale-V4) and P1
                      amplitudes in response to congruent audiovisual stimulus
                      pairs. These results indicate that early visual processing
                      deficits in schizophrenia are apparent during emotion
                      processing but, depending on symptom severity, these
                      deficits can be restored by presenting concurrent
                      emotionally congruent sounds.},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:22977201},
      UT           = {WOS:000336488700006},
      doi          = {10.1093/scan/nss107},
      url          = {https://juser.fz-juelich.de/record/22747},
}